Restenosis or rapid progression in non-dilated sites are not predictors of late spontaneous coronary events

• Published in: International journal of cardiology 1997-07, Vol.60 (2), p.201-211
• Main Authors: Benchimol, Daniel, Dubroca, Bénédicte, Dufourq, Pascale, Benchimol, Hélène, Couffinhal, Thierry, Dartigues, Jean-François, Bonnet, Jacques
• Format: Article
• Language: English
• Subjects: Adult; Aged; Angina Pectoris - diagnostic imaging; Angina Pectoris - surgery; Angioplasty, Balloon, Coronary; Biological and medical sciences; Coronary Disease - diagnostic imaging; Coronary Disease - surgery; Disease Progression; Diseases of the cardiovascular system; Female; Humans; Long-term follow-up; Male; Medical sciences; Middle Aged; Percutaneous transluminal coronary angioplasty; Predictive Value of Tests; Prognostic factors; Progression; Radiography; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Recurrence; Regression Analysis; Restenosis; Retrospective Studies; Risk Factors; Statistics, Nonparametric
• ISSN: 0167-5273; 1874-1754
• DOI: 10.1016/S0167-5273(97)00072-7

The present study was designed to assess the prognostic value of clinical and angiographic factors, and especially restenosis or rapid progression in non-dilated sites, on major spontaneous coronary events at long-term follow-up after a first successful coronary angioplasty performed for angina pectoris. A second aim was to assess the prognostic factors and especially restenosis in asymptomatic patients after angioplasty. The first 352 consecutive patients undergoing a successful coronary angioplasty were selected and followed-up. The following variables: age, sex, unstable angina, previous myocardial infarction, diabetes, hypercholesterolemia, tobacco consumption, hypertension, fibrinogen, coronary extent, single or multiple dilatation, restenosis, new progression, clinical deterioration of anginal status just before angiographic restudy or asymptomatic status were subjected to a stepwise regression analysis. Restenosis (a loss of 30% in diameter and/or a return to a >50% stenosis) and progression in non-dilated segments (a 20% reduction in diameter) were assessed by a computer-assisted method. Cardiac death, new myocardial infarction or new unstable angina, at long-term follow-up after angiographic restudy, were regarded as spontaneous coronary events and pooled in a single dependent variable. Thus 41 patients had a coronary event. In the overall population, clinical deterioration of anginal status ( p