A prospective randomized trial of interstitial radiofrequency therapy versus transurethral resection for the treatment of benign prostatic hyperplasia

• Published in: British Journal of Urology 1997-07, Vol.80 (1), p.116-122
• Main Authors: MOSTAFID, A.H., HARRISON, N.W., THOMAS, P.J., FLETCHER, M.S.
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Benign prostatic hyperplasia; Biological and medical sciences; Catheter Ablation - adverse effects; Catheter Ablation - methods; Diseases of the urinary system; Humans; Male; Medical sciences; Middle Aged; Prospective Studies; Prostatectomy - adverse effects; Prostatectomy - methods; Prostatic Hyperplasia - surgery; radiofrequency; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the urinary system; transurethral resection; Treatment Outcome; Urinary Bladder Neck Obstruction - surgery
• ISSN: 0007-1331; 1464-410X
• DOI: 10.1046/j.1464-410X.1997.00258.x

Objective  To carry out a prospective randomized trial comparing interstitial radiofrequency therapy (IRFT) with transurethral resection of the prostate (TURP) in the treatment of bladder outlet obstruction (BOO) caused by benign prostatic hyperplasia. Patients and methods  The change in detrusor pressure at maximum flow (PdetQmax ) was chosen as the primary measure of outcome but the symptom score, Qmax and residual volume were also measured. Patients with urodynamic evidence of BOO were randomized to receive IRFT (n=25) or TURP (n=25); the urodynamics were repeated 6 months after treatment. Results  There was a statistically significant reduction in PdetQmax at 6 months for TURP (P