Fatty acid acylation of platelet proteins

A variety of fatty acids can become covalently attached to platelet proteins by thioester linkage. These fatty acids include palmitate, myristate, stearate, arachidonate, and eicosapentaenoate. More than 20 platelet proteins can be acylated by fatty acids. Several of the acylated platelet proteins h...

Full description

Saved in:
Bibliographic Details
Published in:Prostaglandins, leukotrienes and essential fatty acids leukotrienes and essential fatty acids, 1997-07, Vol.57 (1), p.33-37
Main Authors: Van Cott, E.M., Muszbek, L., Laposata, M.
Format: Article
Language:English
Subjects:
Acylation
Antigens, CD - metabolism
Biological and medical sciences
Blood coagulation. Blood cells
Blood Platelets - chemistry
Blood Proteins - metabolism
Fatty Acids - metabolism
Fundamental and applied biological sciences. Psychology
GTP-Binding Proteins - metabolism
Humans
Membrane Glycoproteins
Molecular and cellular biology
P-Selectin - metabolism
Platelet
Platelet Glycoprotein GPIb-IX Complex - metabolism
Tetraspanin-29
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A variety of fatty acids can become covalently attached to platelet proteins by thioester linkage. These fatty acids include palmitate, myristate, stearate, arachidonate, and eicosapentaenoate. More than 20 platelet proteins can be acylated by fatty acids. Several of the acylated platelet proteins have been identified, including glycoprotein lbβ, glycoprotein IX, P-selectin, G-protein α subunits, and CD9. This report reviews the fatty acid acylation of platelet proteins.
ISSN:0952-3278
1532-2823
DOI:10.1016/S0952-3278(97)90490-7