Does oligoantigenic diet influence hyperactive/conduct-disordered children--a controlled trial

A crossover 'placebo'-controlled, double-blind design was used to examine the effectiveness of an oligoantigenic diet in 49 children with hyperactive/disruptive behavior disorder. Effects of diet were compared with those yielded by stimulant medication (methylphenidate). The study was cond...

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Bibliographic Details
Published in:European child & adolescent psychiatry 1997-06, Vol.6 (2), p.88-95
Main Authors: Schmidt, M H, Möcks, P, Lay, B, Eisert, H G, Fojkar, R, Fritz-Sigmund, D, Marcus, A, Musaeus, B
Format: Article
Language:English
Subjects:
Attention deficit disorder
Attention Deficit Disorder with Hyperactivity - diet therapy
Behavior change
Central Nervous System Stimulants - therapeutic use
Child
Child & adolescent psychiatry
Child Behavior Disorders - diet therapy
Children
Conduct disorder
Conduct disorders
Cross-Over Studies
Diet
Disruptive behaviour
Double blind studies
Double-Blind Method
Drugs
Female
Food Additives
Germany
Health behavior
Humans
Hyperactive children
Immunoglobulin E - blood
Influences
Inpatient care
Male
Mental disorders
Mental health
Methylphenidate
Methylphenidate - therapeutic use
Severity of Illness Index
Stimulants
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Summary:A crossover 'placebo'-controlled, double-blind design was used to examine the effectiveness of an oligoantigenic diet in 49 children with hyperactive/disruptive behavior disorder. Effects of diet were compared with those yielded by stimulant medication (methylphenidate). The study was conducted in an inpatient unit at the Department of Child and Adolescent Psychiatry, Central Institute of Mental Health, Mannheim. Change in behavior was measured in standardized situations by trained raters, including behavior assessment when testing with CPT and PAT, during a free play situation, and at school. Twelve children (24%) showed significant behavioral improvement in two behavior ratings during diet relative to control diet conditions. Methylphenidate used in 36 children yielded more responders (44%) than diet. The amount of positive changes in behavior in those who received both treatments was about the same. Although only effective in a minority of children, dietary treatment cannot be neglected as a possible access to treating hyperactive/disruptive children and merits further investigation.
ISSN:1018-8827
1435-165X
DOI:10.1007/bf00566671