True Histiocytic Lymphoma as a Second Neoplasm in a Follicular Centroblastic-Centrocytic Lymphoma

We report on a patient who developed a true histiocytic lymphoma, 16 years after initial diagnosis of a follicular low grade centroblastic-centrocytic lymphoma with several recurrences. We consider, out of gene rearrangement and immunohistochemical studies, that in this case, true histiocytic lympho...

Full description

Saved in:
Bibliographic Details
Published in:Pathology, research and practice research and practice, 1997, Vol.193 (4), p.319-322
Main Authors: Rodilla, C. Martin, Aceñero, J. Fernández, Mayor, L. Peña, Carmona, A. Alvarez
Format: Article
Language:English
Subjects:
Antigens, CD - analysis
Antigens, Differentiation, Myelomonocytic - analysis
Fatal Outcome
Humans
Immunohistochemistry
Low grade follicular lymphoma
Lymph Nodes - pathology
Lymphoma, Follicular - immunology
Lymphoma, Follicular - pathology
Lymphoma, Large B-Cell, Diffuse - immunology
Lymphoma, Large B-Cell, Diffuse - pathology
Male
Middle Aged
Mononuclear phagocytic cell
Neoplasms, Second Primary - immunology
Neoplasms, Second Primary - pathology
Reticulum cell sarcoma
Submandibular Gland
True histiocytic lymphoma
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We report on a patient who developed a true histiocytic lymphoma, 16 years after initial diagnosis of a follicular low grade centroblastic-centrocytic lymphoma with several recurrences. We consider, out of gene rearrangement and immunohistochemical studies, that in this case, true histiocytic lymphoma is a second neoplasm in the evolutive course of the low grade lymphoma. The natural history of a low grade malignant lymphoma is to develop into a high grade large cell lymphoma and, if a second neoplasm appears, it is usually an epithelial tumor. This fact makes our report unique, as it would be, to our knowledge, the first case of true histiocytic lymphoma as the second neoplasm of another lymphoma.
ISSN:0344-0338
1618-0631
DOI:10.1016/S0344-0338(97)80010-6