Brush technique in ocular surface cytology

• Published in: Diagnostic cytopathology 1997-08, Vol.17 (2), p.88-91
• Main Authors: Yağmur, Meltem, Ersöz, Canan, Ersöz, T. Reha, Varinli, Seyhan
• Format: Article
• Language: English
• Subjects: Biological and medical sciences; brush technique; Cell Count; Conjunctivitis - pathology; Cytological Techniques; Epithelium - pathology; Eye - cytology; Eye - pathology; Humans; impression cytology; Investigative techniques, diagnostic techniques (general aspects); Keratitis - pathology; Medical sciences; Neutrophils - pathology; ocular cytology; Ophthalmology; Ophthalmology - methods; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; Prospective Studies; Tropical medicine
• ISSN: 8755-1039; 1097-0339
• DOI: 10.1002/(SICI)1097-0339(199708)17:2<88::AID-DC2>3.0.CO;2-K

New techniques are being searched for the evaluation of cellular morphology and population of ocular surface. Impression cytology is one of the most preferred techniques in ocular surface sampling in dry eye, keratitis, and conjunctivitis. We evaluated and compared the efficacy of impression and brush cytology in 63 patients. All of the samples collected by the brush technique were sufficient for diagnosis: 88% of the slides revealed abundant cells and 12% adequate number of cells. In 21% of the samples observed by impression cytology the cell number was inadequate for diagnosis. In 58% of them the cells were abundant and in 21% few cells were observed. This study proved the value of brush cytology in collecting ocular surface cells. Diagn. Cytopathol. 17:88–91, 1997. © 1997 Wiley‐Liss, Inc.