Successful intracytoplasmic sperm injection with spermatozoa from a patient with dysplasia of the fibrous sheath and chronic respiratory disease

The present report describes a successful intracytoplasmic sperm injection (ICSI) procedure performed with immotile spermatozoa from a young man with a combination of dysplasia of the fibrous sheath and dynein deficiency, a recently described variant of the immotile cilia syndrome. This methodology...

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Bibliographic Details
Published in:Human reproduction (Oxford) 1997-07, Vol.12 (7), p.1497-1499
Main Authors: Olmedo, S B, Nodar, F, Chillik, C, Chemes, H E
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Birth control
Chronic Disease
Dyneins - deficiency
Embryo Transfer
Female
Fertilization in Vitro - methods
Gynecology. Andrology. Obstetrics
Humans
Hyperplasia
Hypertrophy
Infertility, Male - etiology
Infertility, Male - therapy
Male
Medical sciences
Microinjections
Pregnancy
Pregnancy Outcome
Respiratory Tract Diseases - complications
Sperm Tail - ultrastructure
Spermatozoa - abnormalities
Spermatozoa - ultrastructure
Sterility. Assisted procreation
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Summary:The present report describes a successful intracytoplasmic sperm injection (ICSI) procedure performed with immotile spermatozoa from a young man with a combination of dysplasia of the fibrous sheath and dynein deficiency, a recently described variant of the immotile cilia syndrome. This methodology provides the only suitable solution for these patients in whom all other assisted fertilization technologies have previously failed, and opens the possibilities for treatment of male infertility due to severe, irreversible sperm defects such as the one reported here.
ISSN:0268-1161
1460-2350
DOI:10.1093/humrep/12.7.1497