Value of QT dispersion in the interpretation of exercise stress test in women

Exercise testing in women is associated with a high incidence of false-positive ECG changes and should be combined with an imaging study. The QT dispersion (QTD), recorded as the difference between maximum and minimum QT intervals on a 12-lead ECG, is sensitive to myocardial ischemia and may improve...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 1997-08, Vol.96 (3), p.904-910
Main Authors: STOLETNIY, L. N, PAI, R. G
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Coronary Angiography
Coronary Disease - diagnosis
Electrocardiography
Electrocardiography. Vectocardiography
Electrodiagnosis. Electric activity recording
Exercise
Exercise Test
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Middle Aged
Reproducibility of Results
Sensitivity and Specificity
Sex Characteristics
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Summary:Exercise testing in women is associated with a high incidence of false-positive ECG changes and should be combined with an imaging study. The QT dispersion (QTD), recorded as the difference between maximum and minimum QT intervals on a 12-lead ECG, is sensitive to myocardial ischemia and may improve the accuracy of exercise testing in women. Exercise ECGs were analyzed in 64 women who had undergone exercise ECG and coronary angiography for clinical indications: 20 patients with normal exercise stress test and nonsignificant (< or = 50% diameter narrowing of a major epicardial coronary artery) coronary artery disease (CAD) on angiography (true-negative; TN group), 20 patients with positive exercise stress tests (> or = 1 mm ST-segment depression or reversible perfusion defects) and significant CAD (true-positive; TP group), and 24 patients with positive exercise stress tests but no significant CAD (false-positive; FP group). The exercise QTD was 45+/-15 ms in TN, 80+/-23 ms in TP (P
ISSN:0009-7322
1524-4539
DOI:10.1161/01.cir.96.3.904