Selenium and vitamin E status of healthy and institutionalized elderly subjects: analysis of plasma, erythrocytes and platelets

Levels of selenium in whole blood, plasma, erythrocytes and platelets, glutathione peroxidase (EC 1.11.1.9; GSH-Px) activity in erythrocytes and platelets and vitamin E, low-density-lipoprotein (LDL)-cholesterol and vitamin E: LDL cholesterol in plasma were measured in seventy-five healthy subjects...

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Bibliographic Details
Published in:British journal of nutrition 1989-07, Vol.62 (1), p.221-227
Main Authors: Campbell, Douglas, Bunker, Valda W., Thomas, Anita J., Clayton, Barbara E.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Aging - blood
Biological and medical sciences
blood
blood plasma
blood platelets
Blood Platelets - analysis
Chronic Disease
elderly
erythrocytes
Erythrocytes - analysis
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
glutathione peroxidase
Glutathione Peroxidase - blood
Hospitalization
Humans
long term care
low density lipoprotein
Male
Middle Aged
nutritional status
Old age
Selenium
Selenium - blood
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Vitamin E
Vitamin E - blood
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Summary:Levels of selenium in whole blood, plasma, erythrocytes and platelets, glutathione peroxidase (EC 1.11.1.9; GSH-Px) activity in erythrocytes and platelets and vitamin E, low-density-lipoprotein (LDL)-cholesterol and vitamin E: LDL cholesterol in plasma were measured in seventy-five healthy subjects aged < 65 years and twenty-eight healthy and twenty-three institutionalized elderly people aged > 65 years. Healthy elderly subjects had significantly lower levels of Se in whole blood and plasma when compared with younger subjects. Other measurements of Se status were not significantly different. In the healthy subjects plasma levels of vitamin E and LDL-cholesterol increased with age to 60 years and decreased above 80 years. Vitamin E: LDL cholesterol values were not affected by age. Measurements of Se and vitamin E status in the institutionalized elderly compared with the healthy elderly were all reduced with the exception of platelet Se levels and erythrocyte GSH-Px activity. Ageing per se had minimal effect on Se and vitamin E status but intercurrent illness and decreased food intake can lead to reduced levels in the elderly.
ISSN:0007-1145
1475-2662
DOI:10.1079/BJN19890022