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Doxapram in hypercapnic chronic obstructive pulmonary disease with respiratory failure
An 81-yr-old man with severe chronic obstructive pulmonary disease and hypercapnia presented to the emergency department (ED) obtunded and in acute respiratory distress. He had instructed his family to refuse intubation but agreed to all other measures to sustain his life. Treatment measures include...
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Published in: | The Journal of emergency medicine 1997-07, Vol.15 (4), p.513-515 |
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container_title | The Journal of emergency medicine |
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creator | KERR, H. D |
description | An 81-yr-old man with severe chronic obstructive pulmonary disease and hypercapnia presented to the emergency department (ED) obtunded and in acute respiratory distress. He had instructed his family to refuse intubation but agreed to all other measures to sustain his life. Treatment measures included the administration of intravenous doxapram, which was followed promptly by a marked improvement in his respiratory function and mentation. Respiratory stimulants may be useful as a temporizing measure in this difficult ED therapeutic problem. |
doi_str_mv | 10.1016/S0736-4679(97)00082-6 |
format | article |
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D</creator><creatorcontrib>KERR, H. D</creatorcontrib><description>An 81-yr-old man with severe chronic obstructive pulmonary disease and hypercapnia presented to the emergency department (ED) obtunded and in acute respiratory distress. He had instructed his family to refuse intubation but agreed to all other measures to sustain his life. Treatment measures included the administration of intravenous doxapram, which was followed promptly by a marked improvement in his respiratory function and mentation. 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D</creatorcontrib><title>Doxapram in hypercapnic chronic obstructive pulmonary disease with respiratory failure</title><title>The Journal of emergency medicine</title><addtitle>J Emerg Med</addtitle><description>An 81-yr-old man with severe chronic obstructive pulmonary disease and hypercapnia presented to the emergency department (ED) obtunded and in acute respiratory distress. He had instructed his family to refuse intubation but agreed to all other measures to sustain his life. Treatment measures included the administration of intravenous doxapram, which was followed promptly by a marked improvement in his respiratory function and mentation. Respiratory stimulants may be useful as a temporizing measure in this difficult ED therapeutic problem.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Central Nervous System Stimulants - therapeutic use</subject><subject>Chronic obstructive pulmonary disease, asthma</subject><subject>Doxapram - therapeutic use</subject><subject>Emergency Service, Hospital</subject><subject>Humans</subject><subject>Hypercapnia - complications</subject><subject>Lung Diseases, Obstructive - complications</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pneumology</subject><subject>Respiratory Insufficiency - drug therapy</subject><subject>Respiratory Insufficiency - etiology</subject><subject>Resuscitation Orders</subject><issn>0736-4679</issn><issn>2352-5029</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><recordid>eNo9kEtLxDAUhYMo4zj6Ewa6ENFF9SZpkmYp4xMGXPjYlts0ZSJ9mbTq_Hs7WGZ1Ft_H4d5DyJLCNQUqb15BcRknUulLra4AIGWxPCBzxgWLBTB9SOZ75ZichPAJQBWkdEZmmimtQMzJx137i53HOnJNtNl21hvsGmcis_HtLts89H4wvfu2UTdUddug30aFCxaDjX5cv4m8DZ3z2LcjKNFVg7en5KjEKtizKRfk_eH-bfUUr18en1e367ijAvqYs1JoWeSMQaFMaXKW2ARQJlwUtEBulNCAWiW52J2uTI6aggSK2piCpXxBLv57O99-DTb0We2CsVWFjW2HkCnNBEjKR3E5iUNe2yLrvKvHR7JpiJGfTxyDwar02BgX9hrj46Bpwv8AjGtuxg</recordid><startdate>199707</startdate><enddate>199707</enddate><creator>KERR, H. 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D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p150t-32f596db220d7cfcb24e40a6435d1da3c7590a974b501707cba910601a9ccd283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Central Nervous System Stimulants - therapeutic use</topic><topic>Chronic obstructive pulmonary disease, asthma</topic><topic>Doxapram - therapeutic use</topic><topic>Emergency Service, Hospital</topic><topic>Humans</topic><topic>Hypercapnia - complications</topic><topic>Lung Diseases, Obstructive - complications</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pneumology</topic><topic>Respiratory Insufficiency - drug therapy</topic><topic>Respiratory Insufficiency - etiology</topic><topic>Resuscitation Orders</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KERR, H. D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of emergency medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KERR, H. D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Doxapram in hypercapnic chronic obstructive pulmonary disease with respiratory failure</atitle><jtitle>The Journal of emergency medicine</jtitle><addtitle>J Emerg Med</addtitle><date>1997-07</date><risdate>1997</risdate><volume>15</volume><issue>4</issue><spage>513</spage><epage>515</epage><pages>513-515</pages><issn>0736-4679</issn><eissn>2352-5029</eissn><coden>JEMMDO</coden><abstract>An 81-yr-old man with severe chronic obstructive pulmonary disease and hypercapnia presented to the emergency department (ED) obtunded and in acute respiratory distress. He had instructed his family to refuse intubation but agreed to all other measures to sustain his life. Treatment measures included the administration of intravenous doxapram, which was followed promptly by a marked improvement in his respiratory function and mentation. Respiratory stimulants may be useful as a temporizing measure in this difficult ED therapeutic problem.</abstract><cop>New York, NY</cop><pub>Elsevier</pub><pmid>9279705</pmid><doi>10.1016/S0736-4679(97)00082-6</doi><tpages>3</tpages></addata></record> |
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subjects | Aged Aged, 80 and over Biological and medical sciences Central Nervous System Stimulants - therapeutic use Chronic obstructive pulmonary disease, asthma Doxapram - therapeutic use Emergency Service, Hospital Humans Hypercapnia - complications Lung Diseases, Obstructive - complications Male Medical sciences Pneumology Respiratory Insufficiency - drug therapy Respiratory Insufficiency - etiology Resuscitation Orders |
title | Doxapram in hypercapnic chronic obstructive pulmonary disease with respiratory failure |
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