Effect of Intravenous Naftidrofuryl on Transcutaneous Oxygen Pressure in Severe Peripheral Vascular Disease

Intravenous naftidrofuryl has been shown to improve transcutaneous oxygen pressure values in patients with severe ischemia of the lower limbs who were considered unsuitable for reconstructive surgery. Although it did not alter the outcome in patients with rest pain, the clinical impression is that i...

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Bibliographic Details
Published in:Angiology 1989-10, Vol.40 (10), p.895-898
Main Authors: Taggart, I., Wishart, G.C., Cuschieri, R.J., MacBain, G.C.
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Blood Gas Monitoring, Transcutaneous
Cardiovascular system
Female
Furans - therapeutic use
Humans
Intermittent Claudication - blood
Intermittent Claudication - drug therapy
Leg - blood supply
Male
Medical sciences
Nafronyl - therapeutic use
Pharmacology. Drug treatments
Random Allocation
Vasodilator agents. Cerebral vasodilators
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Summary:Intravenous naftidrofuryl has been shown to improve transcutaneous oxygen pressure values in patients with severe ischemia of the lower limbs who were considered unsuitable for reconstructive surgery. Although it did not alter the outcome in patients with rest pain, the clinical impression is that it afforded symptomatic relief for a period of time. Clinical implications of these findings require further long-term studies.
ISSN:0003-3197
1940-1574
DOI:10.1177/000331978904001007