The critical first six months in cystic fibrosis: A syndrome of severe bronchiolitis

The syndrome of infantile bronchiolitis in cystic fibrosis (CF) carries a high mortality. Fifteen cases of CF encountered over the past 19 years with severe bronchiolitis with onset during the first 6 months of life are described. Treatment included steroids in high doses. All patients recovered. Fu...

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Bibliographic Details
Published in:Pediatric pulmonology 1997-08, Vol.24 (2), p.134-136
Main Authors: Katznelson, D., Szeinberg, A., Augarten, A., Yahav, Y.
Format: Article
Language:English
Subjects:
bronchiolitis
Bronchiolitis - etiology
corticosteroids
cystic fibrosis
Cystic Fibrosis - complications
Cystic Fibrosis - physiopathology
Cystic Fibrosis - therapy
Female
Humans
Infant
Infant, Newborn
Male
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Summary:The syndrome of infantile bronchiolitis in cystic fibrosis (CF) carries a high mortality. Fifteen cases of CF encountered over the past 19 years with severe bronchiolitis with onset during the first 6 months of life are described. Treatment included steroids in high doses. All patients recovered. Further progress resembled the usual natural course of CF and showed no evidence of persisting lung damage. The mechanism of this syndrome is not clear and is probably dependent on many factors involved in early lung disease in CF. The frequency of severe bronchiolitis in cystic fibrosis may not be high, but it continues to be seen in clinical practice today. Pediatr. Pulmonol. 1997; 24:134–136. © 1997 Wiley‐Liss, Inc.
ISSN:8755-6863
1099-0496
DOI:10.1002/(SICI)1099-0496(199708)24:2<134::AID-PPUL12>3.0.CO;2-3