Retinal wound healing after surgical contusion injury

The lesion was caused by a compression injury to the retina with a vitrectomy instrument in a rhesus monkey; the lesion was examined by electron microscopy 8 years later. The inner surface of the choroid was lined by a layer of cells with the characteristics of fibroblasts. The choriocapillaris was...

Full description

Saved in:
Bibliographic Details
Published in:Graefe's archive for clinical and experimental ophthalmology 1989-01, Vol.227 (5), p.482-488
Main Authors: SPITZNAS, M, KOCH, F, KREIGER, A. E, LUCIANO, L, REALE, E
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Contusions - etiology
Contusions - pathology
Eye Enucleation
Injuries of the orbit. Foreign bodies of the eye. Diseases due to physical agents
Intraoperative Period
Longitudinal Studies
Macaca mulatta
Male
Medical sciences
Microscopy, Electron
Nerve Fibers - ultrastructure
Pigment Epithelium of Eye - pathology
Pigment Epithelium of Eye - ultrastructure
Retina - injuries
Retina - pathology
Retina - ultrastructure
Traumas. Diseases due to physical agents
Vitrectomy - adverse effects
Wound Healing
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The lesion was caused by a compression injury to the retina with a vitrectomy instrument in a rhesus monkey; the lesion was examined by electron microscopy 8 years later. The inner surface of the choroid was lined by a layer of cells with the characteristics of fibroblasts. The choriocapillaris was missing. Bruch's membrane was extremely thickened and showed numerous changes. In the center of the scar, the retinal pigment epithelium was discontinuous. The neuroretinal portion of the scar was composed of distorted and dislocated nerve cells, nerve fibers, and glial elements that were probably Müller cells. Towards the vitreous cavity, the surface of the scar contained numerous microvillous processes. A band of zonulae adherentes resembling the outer limiting membrane was seen immediately adjacent to the surface. No inner limiting membrane was seen in the entire scar area.
ISSN:0721-832X
1435-702X
DOI:10.1007/BF02172903