Human multiunit activity related to attention and preparatory set

The impulse activity of 183 multiunits was recorded from the premotor cortex, the caudate nucleus, the globus pallidus, and the thalamus in 15 Parkinson's disease patients bearing inert gold electrodes implanted for diagnosis and therapy. The patients performed a task in which stimulus triplets...

Full description

Saved in:
Bibliographic Details
Published in:Psychophysiology 1997-09, Vol.34 (5), p.495-500
Main Authors: KROPOTOV, J. D., ETLINGER, S. C., PONOMAREV, V. A.
Format: Article
Language:English
Subjects:
Adult
Attention
Attention - physiology
Basal ganglia-thalamocortical circuits
Brain - cytology
Brain - physiology
Caudate Nucleus - cytology
Caudate Nucleus - physiology
Electric Stimulation Therapy
Electrodes, Implanted
Electroencephalography
Electrophysiology
Female
Globus Pallidus - cytology
Globus Pallidus - physiology
Human multiunit impulse activity
Humans
Male
Middle Aged
Nerve Net - cytology
Nerve Net - physiology
Parkinson Disease - physiopathology
Preparatory set
Set (Psychology)
Thalamus - cytology
Thalamus - physiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The impulse activity of 183 multiunits was recorded from the premotor cortex, the caudate nucleus, the globus pallidus, and the thalamus in 15 Parkinson's disease patients bearing inert gold electrodes implanted for diagnosis and therapy. The patients performed a task in which stimulus triplets (each consisting of two informational and one trigger stimulus) were presented. The patients initiated or inhibited actions (naming or counting) depending on the particular informational stimuli, thus allowing discrimination between different components of multiunit responses associated with attention and preparatory set and with disengagement from these states. The data indicate the existence of two overlapping circuits: one responsible for preparation for and assessment of the behavioral meaning of the stimulus and the other responsible for preparation for and performance of verbal action.
ISSN:0048-5772
1469-8986
DOI:10.1111/j.1469-8986.1997.tb01735.x