Characterization of anti-Toxoplasma activity of SDZ 215-918, a cyclosporin derivative lacking immunosuppressive and peptidyl-prolyl-isomerase-inhibiting activity: possible role of a P glycoprotein in Toxoplasma physiology

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Published in:Antimicrobial Agents and Chemotherapy 1997-09, Vol.41 (9), p.1859-1866
Main Authors: SILVERMAN, J. A, HAYES, M. L, LUFT, B. J, JOINER, K. A
Format: Article
Language:English
Subjects:
Animals
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiparasitic agents
ATP Binding Cassette Transporter, Subfamily B, Member 1
ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors
ATP-Binding Cassette, Sub-Family B, Member 1 - physiology
Biological and medical sciences
Calcium Channel Blockers - pharmacology
Cercopithecus aethiops
Coccidiostats
Coccidiostats - pharmacokinetics
Coccidiostats - pharmacology
Cyclosporine - pharmacology
Cyclosporins
Cyclosporins - pharmacology
Enzyme Inhibitors
Enzyme Inhibitors - pharmacology
Female
Immunosuppressive Agents - pharmacology
Medical sciences
Mice
Peptidylprolyl Isomerase - antagonists & inhibitors
Pharmacology. Drug treatments
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S
Rhodamine 123
Rhodamines - pharmacology
Sensitivity and Specificity
Toxoplasma
Toxoplasma - drug effects
Toxoplasma - growth & development
Toxoplasma - metabolism
Toxoplasma gondii
Verapamil - pharmacology
Vero Cells
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Summary:Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/aac.41.9.1859