Loading…
Ancient DNA is thirteen years old
The first successful recovery of ancient DNA, from quagga and human mummies inspired significant enough interest to open an entire field of research. Efforts from many research groups, often in a hunt for the oldest sequences, showed that ancient DNA was a poor substrate for the enzymes used in mole...
Saved in:
| Published in: | Nature biotechnology 1997-09, Vol.15 (9), p.855-858 |
|---|---|
| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c444t-3f3fe1f2577c37c24d182593957c30e514ace0b6746488ea37d5941a1695bbe63 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c444t-3f3fe1f2577c37c24d182593957c30e514ace0b6746488ea37d5941a1695bbe63 |
| container_end_page | 858 |
| container_issue | 9 |
| container_start_page | 855 |
| container_title | Nature biotechnology |
| container_volume | 15 |
| creator | Audio, Stéphane Béraud-Colomb, Eliane |
| description | The first successful recovery of ancient DNA, from quagga and human mummies inspired significant enough interest to open an entire field of research. Efforts from many research groups, often in a hunt for the oldest sequences, showed that ancient DNA was a poor substrate for the enzymes used in molecular biology; it is present in tiny amounts, hard to purify, and frequently damaged. These obstacles have been partially overcome by the use of drastic laboratory precautions and by the introduction of polymerase chain reaction and phylogenetic studies. Ancient DNA analysis now finds applications in many research domains. |
| doi_str_mv | 10.1038/nbt0997-855 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79305441</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>16060228</sourcerecordid><originalsourceid>FETCH-LOGICAL-c444t-3f3fe1f2577c37c24d182593957c30e514ace0b6746488ea37d5941a1695bbe63</originalsourceid><addsrcrecordid>eNqFkc1LwzAYh4Moc05PnoUOxItWk-arOY75CUMveg5p9lY7unQm7WH_vRktw4t4SsLv4ZeX50XonOBbgml-54oWKyXTnPMDNCaciZQIJQ7jHecyxYSLY3QSwgpjLJgQIzRSFAuq1BhNZ85W4Nrk_nWWVCFpvyrfArhkC8aHpKmXp-ioNHWAs-GcoI_Hh_f5c7p4e3qZzxapZYy1KS1pCaTMuJSWSpuxJckzrqji8Y2BE2Ys4EJIJlieg6FyyRUjJk7KiwIEnaCrvnfjm-8OQqvXVbBQ18ZB0wUt48ycMfIvSAQWOMvyCF73oPVNCB5KvfHV2vitJljvzOnBnI7mIn0x1HbFGpZ7dlAV88shN8GauvQmmgt7LMsJw3Q33U2PhZi4T_B61XTeRXN__DrtcWfazsO-7tdO6Q_rlIxL</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>16060228</pqid></control><display><type>article</type><title>Ancient DNA is thirteen years old</title><source>Nature</source><creator>Audio, Stéphane ; Béraud-Colomb, Eliane</creator><creatorcontrib>Audio, Stéphane ; Béraud-Colomb, Eliane</creatorcontrib><description>The first successful recovery of ancient DNA, from quagga and human mummies inspired significant enough interest to open an entire field of research. Efforts from many research groups, often in a hunt for the oldest sequences, showed that ancient DNA was a poor substrate for the enzymes used in molecular biology; it is present in tiny amounts, hard to purify, and frequently damaged. These obstacles have been partially overcome by the use of drastic laboratory precautions and by the introduction of polymerase chain reaction and phylogenetic studies. Ancient DNA analysis now finds applications in many research domains.</description><identifier>ISSN: 1087-0156</identifier><identifier>EISSN: 1546-1696</identifier><identifier>DOI: 10.1038/nbt0997-855</identifier><identifier>PMID: 9306399</identifier><identifier>CODEN: NABIF9</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>Agriculture ; Animals ; Archaeology ; Bioinformatics ; Biological and medical sciences ; Biological evolution ; Biomedical and Life Sciences ; Biomedical Engineering/Biotechnology ; Biomedicine ; Biotechnology ; Communicable Diseases - genetics ; Diverse techniques ; DNA - chemistry ; DNA - genetics ; DNA, Bacterial - chemistry ; DNA, Bacterial - genetics ; DNA, Plant - chemistry ; DNA, Plant - genetics ; Fundamental and applied biological sciences. Psychology ; Genetic Diseases, Inborn - genetics ; Genetic engineering ; Genetic technics ; Genetics of eukaryotes. Biological and molecular evolution ; Humans ; In vitro gene amplification. Pcr technique ; Life Sciences ; Methods. Procedures. Technologies ; Molecular and cellular biology ; Paleontology ; Polymerase Chain Reaction ; research-review ; Templates, Genetic</subject><ispartof>Nature biotechnology, 1997-09, Vol.15 (9), p.855-858</ispartof><rights>Nature Publishing Company 1997</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-3f3fe1f2577c37c24d182593957c30e514ace0b6746488ea37d5941a1695bbe63</citedby><cites>FETCH-LOGICAL-c444t-3f3fe1f2577c37c24d182593957c30e514ace0b6746488ea37d5941a1695bbe63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2727,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2814031$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9306399$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Audio, Stéphane</creatorcontrib><creatorcontrib>Béraud-Colomb, Eliane</creatorcontrib><title>Ancient DNA is thirteen years old</title><title>Nature biotechnology</title><addtitle>Nat Biotechnol</addtitle><addtitle>Nat Biotechnol</addtitle><description>The first successful recovery of ancient DNA, from quagga and human mummies inspired significant enough interest to open an entire field of research. Efforts from many research groups, often in a hunt for the oldest sequences, showed that ancient DNA was a poor substrate for the enzymes used in molecular biology; it is present in tiny amounts, hard to purify, and frequently damaged. These obstacles have been partially overcome by the use of drastic laboratory precautions and by the introduction of polymerase chain reaction and phylogenetic studies. Ancient DNA analysis now finds applications in many research domains.</description><subject>Agriculture</subject><subject>Animals</subject><subject>Archaeology</subject><subject>Bioinformatics</subject><subject>Biological and medical sciences</subject><subject>Biological evolution</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedical Engineering/Biotechnology</subject><subject>Biomedicine</subject><subject>Biotechnology</subject><subject>Communicable Diseases - genetics</subject><subject>Diverse techniques</subject><subject>DNA - chemistry</subject><subject>DNA - genetics</subject><subject>DNA, Bacterial - chemistry</subject><subject>DNA, Bacterial - genetics</subject><subject>DNA, Plant - chemistry</subject><subject>DNA, Plant - genetics</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genetic Diseases, Inborn - genetics</subject><subject>Genetic engineering</subject><subject>Genetic technics</subject><subject>Genetics of eukaryotes. Biological and molecular evolution</subject><subject>Humans</subject><subject>In vitro gene amplification. Pcr technique</subject><subject>Life Sciences</subject><subject>Methods. Procedures. Technologies</subject><subject>Molecular and cellular biology</subject><subject>Paleontology</subject><subject>Polymerase Chain Reaction</subject><subject>research-review</subject><subject>Templates, Genetic</subject><issn>1087-0156</issn><issn>1546-1696</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><recordid>eNqFkc1LwzAYh4Moc05PnoUOxItWk-arOY75CUMveg5p9lY7unQm7WH_vRktw4t4SsLv4ZeX50XonOBbgml-54oWKyXTnPMDNCaciZQIJQ7jHecyxYSLY3QSwgpjLJgQIzRSFAuq1BhNZ85W4Nrk_nWWVCFpvyrfArhkC8aHpKmXp-ioNHWAs-GcoI_Hh_f5c7p4e3qZzxapZYy1KS1pCaTMuJSWSpuxJckzrqji8Y2BE2Ys4EJIJlieg6FyyRUjJk7KiwIEnaCrvnfjm-8OQqvXVbBQ18ZB0wUt48ycMfIvSAQWOMvyCF73oPVNCB5KvfHV2vitJljvzOnBnI7mIn0x1HbFGpZ7dlAV88shN8GauvQmmgt7LMsJw3Q33U2PhZi4T_B61XTeRXN__DrtcWfazsO-7tdO6Q_rlIxL</recordid><startdate>19970901</startdate><enddate>19970901</enddate><creator>Audio, Stéphane</creator><creator>Béraud-Colomb, Eliane</creator><general>Nature Publishing Group US</general><general>Nature</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7TM</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19970901</creationdate><title>Ancient DNA is thirteen years old</title><author>Audio, Stéphane ; Béraud-Colomb, Eliane</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-3f3fe1f2577c37c24d182593957c30e514ace0b6746488ea37d5941a1695bbe63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Agriculture</topic><topic>Animals</topic><topic>Archaeology</topic><topic>Bioinformatics</topic><topic>Biological and medical sciences</topic><topic>Biological evolution</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedical Engineering/Biotechnology</topic><topic>Biomedicine</topic><topic>Biotechnology</topic><topic>Communicable Diseases - genetics</topic><topic>Diverse techniques</topic><topic>DNA - chemistry</topic><topic>DNA - genetics</topic><topic>DNA, Bacterial - chemistry</topic><topic>DNA, Bacterial - genetics</topic><topic>DNA, Plant - chemistry</topic><topic>DNA, Plant - genetics</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Genetic Diseases, Inborn - genetics</topic><topic>Genetic engineering</topic><topic>Genetic technics</topic><topic>Genetics of eukaryotes. Biological and molecular evolution</topic><topic>Humans</topic><topic>In vitro gene amplification. Pcr technique</topic><topic>Life Sciences</topic><topic>Methods. Procedures. Technologies</topic><topic>Molecular and cellular biology</topic><topic>Paleontology</topic><topic>Polymerase Chain Reaction</topic><topic>research-review</topic><topic>Templates, Genetic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Audio, Stéphane</creatorcontrib><creatorcontrib>Béraud-Colomb, Eliane</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Nature biotechnology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Audio, Stéphane</au><au>Béraud-Colomb, Eliane</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ancient DNA is thirteen years old</atitle><jtitle>Nature biotechnology</jtitle><stitle>Nat Biotechnol</stitle><addtitle>Nat Biotechnol</addtitle><date>1997-09-01</date><risdate>1997</risdate><volume>15</volume><issue>9</issue><spage>855</spage><epage>858</epage><pages>855-858</pages><issn>1087-0156</issn><eissn>1546-1696</eissn><coden>NABIF9</coden><abstract>The first successful recovery of ancient DNA, from quagga and human mummies inspired significant enough interest to open an entire field of research. Efforts from many research groups, often in a hunt for the oldest sequences, showed that ancient DNA was a poor substrate for the enzymes used in molecular biology; it is present in tiny amounts, hard to purify, and frequently damaged. These obstacles have been partially overcome by the use of drastic laboratory precautions and by the introduction of polymerase chain reaction and phylogenetic studies. Ancient DNA analysis now finds applications in many research domains.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><pmid>9306399</pmid><doi>10.1038/nbt0997-855</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1087-0156 |
| ispartof | Nature biotechnology, 1997-09, Vol.15 (9), p.855-858 |
| issn | 1087-0156 1546-1696 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79305441 |
| source | Nature |
| subjects | Agriculture Animals Archaeology Bioinformatics Biological and medical sciences Biological evolution Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biotechnology Communicable Diseases - genetics Diverse techniques DNA - chemistry DNA - genetics DNA, Bacterial - chemistry DNA, Bacterial - genetics DNA, Plant - chemistry DNA, Plant - genetics Fundamental and applied biological sciences. Psychology Genetic Diseases, Inborn - genetics Genetic engineering Genetic technics Genetics of eukaryotes. Biological and molecular evolution Humans In vitro gene amplification. Pcr technique Life Sciences Methods. Procedures. Technologies Molecular and cellular biology Paleontology Polymerase Chain Reaction research-review Templates, Genetic |
| title | Ancient DNA is thirteen years old |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T02%3A51%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Ancient%20DNA%20is%20thirteen%20years%20old&rft.jtitle=Nature%20biotechnology&rft.au=Audio,%20St%C3%A9phane&rft.date=1997-09-01&rft.volume=15&rft.issue=9&rft.spage=855&rft.epage=858&rft.pages=855-858&rft.issn=1087-0156&rft.eissn=1546-1696&rft.coden=NABIF9&rft_id=info:doi/10.1038/nbt0997-855&rft_dat=%3Cproquest_cross%3E16060228%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c444t-3f3fe1f2577c37c24d182593957c30e514ace0b6746488ea37d5941a1695bbe63%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=16060228&rft_id=info:pmid/9306399&rfr_iscdi=true |