Relations of left ventricular mass to demographic and hemodynamic variables in American Indians : The strong heart study

Previous studies have identified associations of left ventricular (LV) mass with demographic (body habitus and sex) and hemodynamic variables (blood pressure, stroke volume [SV], and myocardial contractility), but the relative strength and independence of these associations remain unknown. We examin...

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Published in:Circulation (New York, N.Y.) N.Y.), 1997-09, Vol.96 (5), p.1416-1423
Main Authors: DEVEREUX, R. B, ROMAN, M. J, DE SIMONE, G, O'GRADY, M. J, PARANICAS, M, YEH, J, FABSITZ, R. R, HOWARD, B. V
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
Blood Pressure
Demography
Echocardiography
Female
Fundamental and applied biological sciences. Psychology
Hemodynamics
Hemodynamics. Rheology
Humans
Indians, North American
Male
Middle Aged
Multivariate Analysis
Myocardial Contraction
Rest
Stroke Volume
Ventricular Function, Left
Vertebrates: cardiovascular system
Citations: Items that this one cites
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Summary:Previous studies have identified associations of left ventricular (LV) mass with demographic (body habitus and sex) and hemodynamic variables (blood pressure, stroke volume [SV], and myocardial contractility), but the relative strength and independence of these associations remain unknown. We examined the relations of echocardiographically determined LV mass to demographic variables, blood pressure, Doppler SV, and measures of contractility (end-systolic stress [ESS]/end-systolic volume index and midwall fractional shortening [MFS] as a percentage of predicted for circumferential end-systolic stress [stress-independent shortening]) in 1935 American Indian participants in the Strong Heart Study phase 2 examination without mitral regurgitation or segmental wall motion abnormalities. Weak positive relations of LV mass with systolic and diastolic pressures (r=.22 and r=.20) were exceeded by positive relations with height (r=.30), weight (r=.47), body mass index (r=.31), body surface area (r=.49), and Doppler SV (r=.50) and negative relations with ESS/volume index ratios (r= -.33 and -.29) and stress-independent MFS (r= -.26, all P
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.96.5.1416