High resolution MR technique in the diagnosis of mesial temporal sclerosis correlative MRI and pathological features

Mesial temporal sclerosis, otherwise known as hippocampal sclerosis, is the most common entity associated with medically intractable temporal lobe epilepsy. The neuronal loss and gliosis of the hippocampus that is pathologically characteristic of this disorder is thought to serve as an epileptogenic...

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Bibliographic Details
Published in:Clinical imaging 1997-09, Vol.21 (5), p.319-322
Main Authors: Wasenko, John J., Gharagozloo, Ali M., Smith, Mark V., Thomas, Dafydd
Format: Article
Language:English
Subjects:
Adult
Amygdala - pathology
Amygdala - surgery
Biological and medical sciences
Brain Mapping
Epilepsy, Temporal Lobe - diagnosis
Epilepsy, Temporal Lobe - surgery
Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
Hippocampus
Hippocampus - pathology
Hippocampus - surgery
Humans
Magnetic resonance
Magnetic Resonance Imaging
Male
Medical sciences
Mesial temporal sclerosis
Nervous system (semeiology, syndromes)
Neurology
Psychosurgery
Sclerosis
Seizure
Temporal Lobe - pathology
Temporal Lobe - surgery
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Summary:Mesial temporal sclerosis, otherwise known as hippocampal sclerosis, is the most common entity associated with medically intractable temporal lobe epilepsy. The neuronal loss and gliosis of the hippocampus that is pathologically characteristic of this disorder is thought to serve as an epileptogenic substrate. Accurate identification and localization of this pathology is crucial before surgery is considered to potentially cure medically intractable seizures. Magnetic resonance imaging plays a central role in the presurgical work-up. We present a 44-year-old man with a history of intractable partial complex seizures secondary to right-sided mesial temporal sclerosis and discuss the magnetic resonance imaging findings utilizing a high resolution technique.
ISSN:0899-7071
1873-4499
DOI:10.1016/S0899-7071(96)00089-7