Leukocyte adhesion: CD11/CD18 integrins and intercellular adhesion molecules

Leukocyte integrins and intercellular adhesion molecules play pivotal roles in leukocyte adhesion to target cells and extracellular matrices. Recently, novel intercellular adhesion molecules have been identified, and much information has been obtained on the structures and binding sites of leukocyte...

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Bibliographic Details
Published in:Current opinion in cell biology 1997-10, Vol.9 (5), p.643-650
Main Author: Gahmberg, Carl G
Format: Article
Language:English
Subjects:
Animals
CD18 Antigens - physiology
Cell Adhesion - physiology
Cell Adhesion Molecules - physiology
Humans
Integrins - physiology
Leukocytes - cytology
Lymphocyte Function-Associated Antigen-1 - physiology
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Summary:Leukocyte integrins and intercellular adhesion molecules play pivotal roles in leukocyte adhesion to target cells and extracellular matrices. Recently, novel intercellular adhesion molecules have been identified, and much information has been obtained on the structures and binding sites of leukocyte integrins and of intercellular adhesion molecules. Furthermore, much progress has been made in the study of integrin activation and the role of leukocyte adhesion molecules in disease.
ISSN:0955-0674
1879-0410
DOI:10.1016/S0955-0674(97)80117-2