Reconstruction of ureteral defects with a tubular skin graft secondarily prefabricated utilizing omentum as a carrier: An experimental study

• Published in: Urology (Ridgewood, N.J.) N.J.), 1997-10, Vol.50 (4), p.625-629
• Main Authors: Özdemir, O. Gürhan, Güneş, Zek E., Gemalmaz, Hakan, Saray, Aydin, Özdemir, B. Handan, Arda, Kemal
• Format: Article
• Language: English
• Subjects: Animals; Biological and medical sciences; Dogs; Female; Medical sciences; Omentum - transplantation; Skin Transplantation - methods; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the urinary system; Ureter - injuries; Ureter - surgery
• ISSN: 0090-4295; 1527-9995
• DOI: 10.1016/S0090-4295(97)00400-7

This study was conducted to evaluate reconstruction of the ureter in dogs after resection of a 7-cm-long midlength segment with a vascularized tubular skin graft secondarily prefabricated utilizing omenturn as a carrier. Nine female mongrel dogs underwent surgery in which omental surface capabilities were used to create a vascularized prefabricated skin graft. After 4 weeks, all 9 dogs underwent the second surgical procedure, which included the resection of a 7-cm-long segment from the ureter and an interureteral anastomosis of the omentocutaneous cylindrical tube. At postoperative week 10, just before the third surgical procedure, intravenous urography was performed to evaluate the continuity of the treated ureter. Nephroureterectomy was also performed immediately after intravenous urography to obtain specimens for histologic analysis of the aforementioned tubular anastomosis. The continuity of the ureteral defect was restored with the help of the omentocutaneous cylindrical tube. There was no narrowing throughout the ureter and along the omentocutaneous cylindrical tube. Only minimal dilation occurred at the neoskin tube and at the ipsilateral collecting system. Histopathologically, there were capillary protrusions entering the skin graft from the omental vasculature. The columnar epithelium of the cutaneous cylindrical tube was completely preserved, and transitional ingrowth was present at the proximal and distal ends of the tube. The surgical procedure resulted in successful reconstruction of ureteral continuity by the use of a prefabricated omentocutaneous cylindrical tube in dogs.