Specimen mammography-guided fine-needle aspirates of mammographically normal fatty and dense benign tissue : Analysis of cell number and type

Specimen mammography-guided 20-gauge fine-needle aspirates (FNA) were obtained from normal dense or fatty tissue. Single aspirates of dense tissue yielded greater cell counts; 74% (32 of 43) had greater than 5,000 cells as compared to 20% (19 of 93) of fatty tissue FNA, p < 0.05. Dense tissue FNA...

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Bibliographic Details
Published in:Breast cancer research and treatment 1997-09, Vol.45 (2), p.135-139
Main Authors: STOMPER, P. C, NAVA, M. E. R, BUDNICK, R. M, STEWART, C. C
Format: Article
Language:English
Subjects:
Age Factors
Biological and medical sciences
Biopsy, Needle - methods
Breast - pathology
Breast cancer
Cancer research
Cell Count
Diverse techniques
Epithelium - pathology
Female
Fundamental and applied biological sciences. Psychology
Humans
Mammography
Middle Aged
Molecular and cellular biology
Radiography, Interventional
Stromal Cells - pathology
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Summary:Specimen mammography-guided 20-gauge fine-needle aspirates (FNA) were obtained from normal dense or fatty tissue. Single aspirates of dense tissue yielded greater cell counts; 74% (32 of 43) had greater than 5,000 cells as compared to 20% (19 of 93) of fatty tissue FNA, p < 0.05. Dense tissue FNA also yielded greater percentages of epithelial cells; 95% (21 of 22) had greater than 50% epithelial cells as compared to 43% (17 of 40) of fatty tissue FNA, p < 0.05. Mammographic guidance toward dense tissue is suggested for clinical studies of risk assessment using FNA of normal breast tissue.
ISSN:0167-6806
1573-7217
DOI:10.1023/A:1005818117347