Immunolocalization of the Inducible Nitric Oxide Synthase Isoform in Human Fetal Membranes

PROBLEM: Nitric oxide (NO) synthesized by fetal membranes may protect the fetus from maternal infection or immune challenge or have a tocolytic effect on myometrium. The sites of synthesis and enzymes responsible for NO production in human fetal membranes remain unidentified. METHOD OF STUDY: Fetal...

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Bibliographic Details
Published in:American journal of reproductive immunology (1989) 1997-10, Vol.38 (4), p.289-294
Main Authors: Eis, A.L.W., Brockman, D.E., Myatt, L.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Chorioamnionitis
Embryology: invertebrates and vertebrates. Teratology
Endothelium, Vascular - enzymology
Endothelium, Vascular - immunology
Extraembryonic Membranes - blood supply
Extraembryonic Membranes - enzymology
Extraembryonic Membranes - immunology
Female
Fetal membranes
fibroblast
Fundamental and applied biological sciences. Psychology
General aspects. Development. Fetal membranes
Humans
Immunohistochemistry
In Vitro Techniques
Infant, Newborn
labor
Labor, Obstetric - immunology
Labor, Obstetric - metabolism
Lipopolysaccharide Receptors - metabolism
macrophage
nitric oxide
Nitric Oxide Synthase - immunology
Nitric Oxide Synthase - metabolism
Obstetric Labor, Premature - enzymology
Obstetric Labor, Premature - immunology
parturition
Pregnancy
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Summary:PROBLEM: Nitric oxide (NO) synthesized by fetal membranes may protect the fetus from maternal infection or immune challenge or have a tocolytic effect on myometrium. The sites of synthesis and enzymes responsible for NO production in human fetal membranes remain unidentified. METHOD OF STUDY: Fetal membranes were obtained from four groups of patients: term (>37 weeks gestation) or preterm (
ISSN:1046-7408
8755-8920
1600-0897
DOI:10.1111/j.1600-0897.1997.tb00517.x