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Invasive Aspergillus sinusitis During Bone Marrow Transplantation
Aspergillus sinusitis is usually a lethal condition in bone marrow transplanted patients. We report the case of a patient known to have a sinus infection with Aspergillus flavus before treatment with allogenic bone marrow transplantation for a refractory-acute myelogenous leukemia. Exacerbation of t...
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| Published in: | Scandinavian journal of infectious diseases 1997, Vol.29 (4), p.436-438 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c408t-64c25f791d74c6129bd4a6153ea49f61fecb05970f3639686590f6cd6dfe03653 |
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| cites | cdi_FETCH-LOGICAL-c408t-64c25f791d74c6129bd4a6153ea49f61fecb05970f3639686590f6cd6dfe03653 |
| container_end_page | 438 |
| container_issue | 4 |
| container_start_page | 436 |
| container_title | Scandinavian journal of infectious diseases |
| container_volume | 29 |
| creator | Verschraegen, Claire F. Van Besien, Koen W. Dignani, Cecilia Hester, Jeane P. Andersson, Borje S. Anaissie, Elias |
| description | Aspergillus sinusitis is usually a lethal condition in bone marrow transplanted patients. We report the case of a patient known to have a sinus infection with Aspergillus flavus before treatment with allogenic bone marrow transplantation for a refractory-acute myelogenous leukemia. Exacerbation of the sinusitis during the neutropenic period required a multidisciplinary approach. Cure was achieved after treatment with a combination of surgery (Caldwell-Luc procedure), long term ABCD (amphotericin B colloidal dispersion) therapy (7 months) and granulocyte transfusions during the period preceding engraftment. The use of granulocyte transfusion in this salvage setting is discussed. Aggressive multimodality management of aspergillus sinusitis in immunosuppressed patients may lead to a cure and might not preclude allogenic transplantation. |
| doi_str_mv | 10.3109/00365549709011849 |
| format | article |
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We report the case of a patient known to have a sinus infection with Aspergillus flavus before treatment with allogenic bone marrow transplantation for a refractory-acute myelogenous leukemia. Exacerbation of the sinusitis during the neutropenic period required a multidisciplinary approach. Cure was achieved after treatment with a combination of surgery (Caldwell-Luc procedure), long term ABCD (amphotericin B colloidal dispersion) therapy (7 months) and granulocyte transfusions during the period preceding engraftment. The use of granulocyte transfusion in this salvage setting is discussed. Aggressive multimodality management of aspergillus sinusitis in immunosuppressed patients may lead to a cure and might not preclude allogenic transplantation.</description><identifier>ISSN: 0036-5548</identifier><identifier>EISSN: 1651-1980</identifier><identifier>DOI: 10.3109/00365549709011849</identifier><identifier>PMID: 9360268</identifier><identifier>CODEN: SJIDB7</identifier><language>eng</language><publisher>Basingstoke: Informa UK Ltd</publisher><subject>Adult ; Amphotericin B - administration & dosage ; Amphotericin B - therapeutic use ; Antifungal Agents - administration & dosage ; Antifungal Agents - therapeutic use ; Aspergillosis - complications ; Aspergillosis - diagnosis ; Aspergillosis - drug therapy ; Biological and medical sciences ; Bone Marrow Transplantation - adverse effects ; Ent and stomatologic mycoses ; Female ; Granulocytes ; Human mycoses ; Humans ; Immunocompromised Host ; Infectious diseases ; Leukemia, Myeloid, Acute - complications ; Leukocyte Transfusion ; Medical sciences ; Mycoses ; Neutropenia - microbiology ; Sinusitis - complications ; Sinusitis - microbiology ; Sinusitis - surgery</subject><ispartof>Scandinavian journal of infectious diseases, 1997, Vol.29 (4), p.436-438</ispartof><rights>1997 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1997</rights><rights>1997 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-64c25f791d74c6129bd4a6153ea49f61fecb05970f3639686590f6cd6dfe03653</citedby><cites>FETCH-LOGICAL-c408t-64c25f791d74c6129bd4a6153ea49f61fecb05970f3639686590f6cd6dfe03653</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4021,27921,27922,27923</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2840070$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9360268$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Verschraegen, Claire F.</creatorcontrib><creatorcontrib>Van Besien, Koen W.</creatorcontrib><creatorcontrib>Dignani, Cecilia</creatorcontrib><creatorcontrib>Hester, Jeane P.</creatorcontrib><creatorcontrib>Andersson, Borje S.</creatorcontrib><creatorcontrib>Anaissie, Elias</creatorcontrib><title>Invasive Aspergillus sinusitis During Bone Marrow Transplantation</title><title>Scandinavian journal of infectious diseases</title><addtitle>Scand J Infect Dis</addtitle><description>Aspergillus sinusitis is usually a lethal condition in bone marrow transplanted patients. We report the case of a patient known to have a sinus infection with Aspergillus flavus before treatment with allogenic bone marrow transplantation for a refractory-acute myelogenous leukemia. Exacerbation of the sinusitis during the neutropenic period required a multidisciplinary approach. Cure was achieved after treatment with a combination of surgery (Caldwell-Luc procedure), long term ABCD (amphotericin B colloidal dispersion) therapy (7 months) and granulocyte transfusions during the period preceding engraftment. The use of granulocyte transfusion in this salvage setting is discussed. Aggressive multimodality management of aspergillus sinusitis in immunosuppressed patients may lead to a cure and might not preclude allogenic transplantation.</description><subject>Adult</subject><subject>Amphotericin B - administration & dosage</subject><subject>Amphotericin B - therapeutic use</subject><subject>Antifungal Agents - administration & dosage</subject><subject>Antifungal Agents - therapeutic use</subject><subject>Aspergillosis - complications</subject><subject>Aspergillosis - diagnosis</subject><subject>Aspergillosis - drug therapy</subject><subject>Biological and medical sciences</subject><subject>Bone Marrow Transplantation - adverse effects</subject><subject>Ent and stomatologic mycoses</subject><subject>Female</subject><subject>Granulocytes</subject><subject>Human mycoses</subject><subject>Humans</subject><subject>Immunocompromised Host</subject><subject>Infectious diseases</subject><subject>Leukemia, Myeloid, Acute - complications</subject><subject>Leukocyte Transfusion</subject><subject>Medical sciences</subject><subject>Mycoses</subject><subject>Neutropenia - microbiology</subject><subject>Sinusitis - complications</subject><subject>Sinusitis - microbiology</subject><subject>Sinusitis - surgery</subject><issn>0036-5548</issn><issn>1651-1980</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><recordid>eNqFkD1PwzAQhi0EKuXjBzAgZUBsgXPsOLGYSvmqVMRS5sh17GKUOsWXFPHvcdWKBQmmG97nPd09hJxRuGIU5DUAE3nOZQESKC253CNDKnKaUlnCPhlu8jQC5SE5QnwHAC4YDMhAMgGZKIdkNPFrhW5tkhGuTFi4pukxQed7dJ3D5K4Pzi-S29ab5FmF0H4ms6A8rhrlO9W51p-QA6saNKe7eUxeH-5n46d0-vI4GY-mqeZQdqngOsttIWldcC1oJuc1V4LmzCguraDW6Dnk8RPLBJOiFLkEK3Qtams2X7JjcrnduwrtR2-wq5YOtWniIabtsSokk7nIin9BKlgWPdAI0i2oQ4sYjK1WwS1V-KooVBu_1S-_sXO-W97Pl6b-aeyExvxilyvUqrHRlXb4g2UlByggYjdbzHnbhqV6M6rp3rQKpnpv--CjyD-O-Aby_ZOl</recordid><startdate>1997</startdate><enddate>1997</enddate><creator>Verschraegen, Claire F.</creator><creator>Van Besien, Koen W.</creator><creator>Dignani, Cecilia</creator><creator>Hester, Jeane P.</creator><creator>Andersson, Borje S.</creator><creator>Anaissie, Elias</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>1997</creationdate><title>Invasive Aspergillus sinusitis During Bone Marrow Transplantation</title><author>Verschraegen, Claire F. ; Van Besien, Koen W. ; Dignani, Cecilia ; Hester, Jeane P. ; Andersson, Borje S. ; Anaissie, Elias</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-64c25f791d74c6129bd4a6153ea49f61fecb05970f3639686590f6cd6dfe03653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>Amphotericin B - administration & dosage</topic><topic>Amphotericin B - therapeutic use</topic><topic>Antifungal Agents - administration & dosage</topic><topic>Antifungal Agents - therapeutic use</topic><topic>Aspergillosis - complications</topic><topic>Aspergillosis - diagnosis</topic><topic>Aspergillosis - drug therapy</topic><topic>Biological and medical sciences</topic><topic>Bone Marrow Transplantation - adverse effects</topic><topic>Ent and stomatologic mycoses</topic><topic>Female</topic><topic>Granulocytes</topic><topic>Human mycoses</topic><topic>Humans</topic><topic>Immunocompromised Host</topic><topic>Infectious diseases</topic><topic>Leukemia, Myeloid, Acute - complications</topic><topic>Leukocyte Transfusion</topic><topic>Medical sciences</topic><topic>Mycoses</topic><topic>Neutropenia - microbiology</topic><topic>Sinusitis - complications</topic><topic>Sinusitis - microbiology</topic><topic>Sinusitis - surgery</topic><toplevel>online_resources</toplevel><creatorcontrib>Verschraegen, Claire F.</creatorcontrib><creatorcontrib>Van Besien, Koen W.</creatorcontrib><creatorcontrib>Dignani, Cecilia</creatorcontrib><creatorcontrib>Hester, Jeane P.</creatorcontrib><creatorcontrib>Andersson, Borje S.</creatorcontrib><creatorcontrib>Anaissie, Elias</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Verschraegen, Claire F.</au><au>Van Besien, Koen W.</au><au>Dignani, Cecilia</au><au>Hester, Jeane P.</au><au>Andersson, Borje S.</au><au>Anaissie, Elias</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Invasive Aspergillus sinusitis During Bone Marrow Transplantation</atitle><jtitle>Scandinavian journal of infectious diseases</jtitle><addtitle>Scand J Infect Dis</addtitle><date>1997</date><risdate>1997</risdate><volume>29</volume><issue>4</issue><spage>436</spage><epage>438</epage><pages>436-438</pages><issn>0036-5548</issn><eissn>1651-1980</eissn><coden>SJIDB7</coden><abstract>Aspergillus sinusitis is usually a lethal condition in bone marrow transplanted patients. We report the case of a patient known to have a sinus infection with Aspergillus flavus before treatment with allogenic bone marrow transplantation for a refractory-acute myelogenous leukemia. Exacerbation of the sinusitis during the neutropenic period required a multidisciplinary approach. Cure was achieved after treatment with a combination of surgery (Caldwell-Luc procedure), long term ABCD (amphotericin B colloidal dispersion) therapy (7 months) and granulocyte transfusions during the period preceding engraftment. The use of granulocyte transfusion in this salvage setting is discussed. Aggressive multimodality management of aspergillus sinusitis in immunosuppressed patients may lead to a cure and might not preclude allogenic transplantation.</abstract><cop>Basingstoke</cop><pub>Informa UK Ltd</pub><pmid>9360268</pmid><doi>10.3109/00365549709011849</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-5548 |
| ispartof | Scandinavian journal of infectious diseases, 1997, Vol.29 (4), p.436-438 |
| issn | 0036-5548 1651-1980 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79395627 |
| source | Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list) |
| subjects | Adult Amphotericin B - administration & dosage Amphotericin B - therapeutic use Antifungal Agents - administration & dosage Antifungal Agents - therapeutic use Aspergillosis - complications Aspergillosis - diagnosis Aspergillosis - drug therapy Biological and medical sciences Bone Marrow Transplantation - adverse effects Ent and stomatologic mycoses Female Granulocytes Human mycoses Humans Immunocompromised Host Infectious diseases Leukemia, Myeloid, Acute - complications Leukocyte Transfusion Medical sciences Mycoses Neutropenia - microbiology Sinusitis - complications Sinusitis - microbiology Sinusitis - surgery |
| title | Invasive Aspergillus sinusitis During Bone Marrow Transplantation |
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