Polymorphisms of HPA-1 Through 6 on Platelet Membrane Glycoprotein Receptors Are Not a Genetic Risk Factor for Myocardial Infarction in the Japanese Population

We examined HPA genotypes derived from polymorphisms of platelet membrane receptors in 88 Japanese patients with early-onset myocardial infarction and in 100 control subjects. The results indicated that HPA genotypes 1 through 6 are not associated with early-onset myocardial infarction.

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Bibliographic Details
Published in:The American journal of cardiology 1997-11, Vol.80 (9), p.1222-1224
Main Authors: Hato, Takaaki, Minamoto, Yoko, Fukuyama, Takaya, Fujita, Shigeru
Format: Article
Language:English
Subjects:
Antigens, Human Platelet - genetics
Biological and medical sciences
Cardiology. Vascular system
Case-Control Studies
Coronary heart disease
Female
Genetics
Genotype
Heart
Heart attacks
Humans
Male
Medical sciences
Membranes
Middle Aged
Myocardial Infarction - ethnology
Myocardial Infarction - genetics
Platelet Glycoprotein GPIIb-IIIa Complex - genetics
Platelet Membrane Glycoproteins - genetics
Polymerase Chain Reaction
Polymorphism, Genetic
Proteins
Risk Factors
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Description
Summary:We examined HPA genotypes derived from polymorphisms of platelet membrane receptors in 88 Japanese patients with early-onset myocardial infarction and in 100 control subjects. The results indicated that HPA genotypes 1 through 6 are not associated with early-onset myocardial infarction.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(97)00645-0