Gastric dysrhythmias and delayed gastric emptying in patients with functional dyspepsia

An association between dyspepsia, gastric motility disorders, and myoelectrical abnormalities has been noted. The objective of the present study was to investigate both antral myoelectrical activity and gastric emptying in patients with functional dyspepsia (FD). Electrogastrography (EGG) was perfor...

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Bibliographic Details
Published in:Digestive diseases and sciences 1997-10, Vol.42 (10), p.2094-2099
Main Authors: PFAFFENBACH, B, ADAMEK, R. J, BARTHOLOMÄUS, C, WEGENER, M
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Colloids
Digestive tract
Dyspepsia - diagnosis
Dyspepsia - physiopathology
Electrodiagnosis - instrumentation
Electrodiagnosis - methods
Electrodiagnosis - statistics & numerical data
Electrodiagnosis. Electric activity recording
Fasting - physiology
Female
Gastric Emptying
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Periodicity
Postprandial Period - physiology
Radionuclide Imaging
Statistics, Nonparametric
Stomach - diagnostic imaging
Stomach - physiopathology
Technetium
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Summary:An association between dyspepsia, gastric motility disorders, and myoelectrical abnormalities has been noted. The objective of the present study was to investigate both antral myoelectrical activity and gastric emptying in patients with functional dyspepsia (FD). Electrogastrography (EGG) was performed in 25 adult patients with FD, which had been evaluated by score. After an overnight fast, for 1 hr in the pre- and postprandial state (370 kcal liquid-solid test meal) the following EGG parameters were determined: dominant frequency [DF (cpm)], DF (%) in the normal range (2-4 cpm), bradygastria (68%). These patients showed significantly more pre- and postprandial tachygastrias than patients with normal gastric emptying (P < 0.05). The dyspeptic symptomatology and H. pylori status did not correlate with EGG and radioscintigraphy. Patients with FD frequently reveal impaired gastric emptying and increased tachygastria, which may have pathophysiological significance in some of these patients.
ISSN:0163-2116
1573-2568
DOI:10.1023/A:1018826719628