Hormone replacement therapy and intraocular pressure

Objectives: To evaluate the effect of hormone replacement therapy (HRT) on intraocular pressure (IOP) in menopausal women. Methods: The IOP of 25 white menopausal women without an abnormal ophthalmologic history was measured before and during HRT regimen. IOP fluctations were recorded before and 1,...

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Bibliographic Details
Published in:Maturitas 1997-09, Vol.28 (1), p.55-58
Main Authors: Sator, Michael O., Joura, Elmar A., Frigo, Peter, Kurz, Christine, Metka, Markus, Hommer, Anton, Huber, Johannes C.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Estrogen Replacement Therapy
Female
Gynecology. Andrology. Obstetrics
Hormone replacement therapy
Humans
Intraocular pressure
Intraocular Pressure - drug effects
Medical sciences
Menopause
Middle Aged
Nitric oxide
Prospective Studies
Puberal and climacteric disorders (male and female)
Time Factors
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Summary:Objectives: To evaluate the effect of hormone replacement therapy (HRT) on intraocular pressure (IOP) in menopausal women. Methods: The IOP of 25 white menopausal women without an abnormal ophthalmologic history was measured before and during HRT regimen. IOP fluctations were recorded before and 1, 4, and 12 weeks after the beginning of HRT. These measurements were obtained according to a standardized time schedule (08:00, 12:00, 16:00, and 19:00 h). Results: The mean IOP in the left eye decreased from 16.2 ± 2.4 mmHg before therapy to 14.0 ± 2.1 mmHg after 12 weeks of therapy ( P
ISSN:0378-5122
1873-4111
DOI:10.1016/S0378-5122(97)00060-1