Biological aspects of long-term failure of autografts after cruciate ligament replacement

The alterations of the ultrastructure of the posterior cruciate ligament autograft of patellar tendon origin were examined in a sheep model 1 year after surgery. The ultrastructure was also compared with that of the normal contralateral posterior cruciate ligament and patellar tendon. The most strik...

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Bibliographic Details
Published in:Archives of Orthopaedic and Trauma Surgery 1989-01, Vol.108 (6), p.368-372
Main Authors: BOSCH, U, DECKER, B, KASPERCZYK, W, OESTERN, H. J, TSCHERNE, H
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Knee Injuries - surgery
Ligaments, Articular - transplantation
Ligaments, Articular - ultrastructure
Medical sciences
Orthopedic surgery
Sheep
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Transplantation, Homologous
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Summary:The alterations of the ultrastructure of the posterior cruciate ligament autograft of patellar tendon origin were examined in a sheep model 1 year after surgery. The ultrastructure was also compared with that of the normal contralateral posterior cruciate ligament and patellar tendon. The most striking finding was the unimodal distribution of the collagen fibrils, with a predominance of loosely packed thin fibrils in the central portion of the autograft. The results suggested that the remodeled autograft tissue became highly organized but never exhibited the ultrastructural features of a ligament. This could be responsible for the decreased biomechanical properties and the long-term failure of a patellar tendon autograft.
ISSN:0344-8444
0936-8051
1434-3916
DOI:10.1007/BF00932448