Non-African Burkitt Lymphoma Presenting With Oral Thrush and an Orbital Mass in a Child

To report an unusual case of orbital involvement with non-African Burkitt lymphoma in a child. A 26-month-old boy developed oral thrush and painless right proptosis with eyelid swelling. Magnetic resonance imaging disclosed a diffuse mass involving the inferior, lateral, and superior right orbit and...

Full description

Saved in:
Bibliographic Details
Published in:American journal of ophthalmology 1997-12, Vol.124 (6), p.859-861
Main Authors: Edelstein, Chaim, Shields, Jerry A., Shields, Carol L., Potter, Patrick De, Eagle, Ralph C., Turtel, Lawrence, Hagstrom, N.
Format: Article
Language:English
Subjects:
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Biopsy
Burkitt Lymphoma - complications
Burkitt Lymphoma - diagnosis
Burkitt Lymphoma - drug therapy
Candidiasis, Oral - complications
Candidiasis, Oral - diagnosis
Child, Preschool
Diagnosis, Differential
Follow-Up Studies
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Ophthalmology
Orbital Neoplasms - complications
Orbital Neoplasms - diagnosis
Orbital Neoplasms - drug therapy
Tomography, X-Ray Computed
Tumors and pseudotumors of the eye, orbit, eyelid, lacrimal apparatus
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To report an unusual case of orbital involvement with non-African Burkitt lymphoma in a child. A 26-month-old boy developed oral thrush and painless right proptosis with eyelid swelling. Magnetic resonance imaging disclosed a diffuse mass involving the inferior, lateral, and superior right orbit and both maxillary sinuses. Incisional biopsy of the orbital mass was performed. Histopathology disclosed diffuse infiltration of the orbital tissues by a high-grade lymphoid neoplasm that showed positive immuno-reactivity for B-cell markers. Immunoglobulin gene rearrangement studies disclosed a characteristic t(8;14) translocation consistent with a small, noncleaved malignant lymphoma of the Burkitt type. Non-African Burkitt lymphoma may manifest with orbital involvement.
ISSN:0002-9394
1879-1891
DOI:10.1016/S0002-9394(14)71714-3