Risk factors, clinical features and outcome of Acinetobacter bacteremia in adults

• Published in: European journal of clinical microbiology & infectious diseases 1997-10, Vol.16 (10), p.737-740
• Main Authors: POUTANEN, S. M, LOUIE, M, SIMOR, A. E
• Format: Article
• Language: English
• Subjects: Acinetobacter - drug effects; Acinetobacter Infections - diagnosis; Acinetobacter Infections - epidemiology; Acinetobacter Infections - mortality; Adult; Age Factors; Aged; Anti-Bacterial Agents - pharmacology; Bacteremia - complications; Bacteremia - diagnosis; Bacteremia - epidemiology; Bacterial diseases; Bacterial sepsis; Biological and medical sciences; Blood Coagulation Disorders - complications; Cross Infection - microbiology; Female; Human bacterial diseases; Humans; Infectious diseases; Intensive Care Units; Male; Medical sciences; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Risk Factors; Shock, Septic - diagnosis; Shock, Septic - epidemiology; Shock, Septic - mortality
• ISSN: 0934-9723; 1435-4373
• DOI: 10.1007/BF01709254

The medical records of 39 patients with Acinetobacter bacteremia identified in the period between 1985 and 1995 were reviewed. In 24 cases (62%) the bacteremia was considered to have been clinically significant. Most of the infections (79%) were nosocomial, and the majority of these were acquired in an intensive care unit. Ten (42%) patients developed septic shock complicating the bacteremia and 13 (54%) died. In most of these cases (85%), Acinetobacter bacteremia was thought to have caused or contributed to death. The following variables were associated with a greater risk of mortality: age > 65 years (OR = 16; p = 0.01); development of septic shock (OR = 22; p = 0.004); and the presence of coagulopathy (OR = 20; p = 0.03).