Role of DOPA decarboxylase and N-acetyl transferase in regulation of dopamine content in Drosophila virilis under normal and heat stress conditions

Activity levels of DOPA decarboxylase (DDC), an enzyme responsible for dopamine (DA) synthesis, and of N-acetyl transferase (NAT), an enzyme responsible for its degradation, were studied under normal and stress conditions in two lines of Drosophila virilis which are in contrast concerning their DA c...

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Bibliographic Details
Published in:Insect biochemistry and molecular biology 1997-08, Vol.27 (8), p.729-734
Main Authors: Rauschenbach, I.Yu, Sukhanova, M.Jh, Shumnaya, L.V., Gruntenko, N.E., Grenback, L.G., Khlebodarova, T.M., Chentsova, N.A.
Format: Article
Language:English
Subjects:
Acetyltransferases - metabolism
Animals
DOPA decarboxylase
Dopa Decarboxylase - metabolism
dopamine
Dopamine - metabolism
Drosophila - enzymology
Drosophila - genetics
Drosophila virilis
Female
heat stress
Hot Temperature
Male
N-acetyl transferase
Time Factors
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Summary:Activity levels of DOPA decarboxylase (DDC), an enzyme responsible for dopamine (DA) synthesis, and of N-acetyl transferase (NAT), an enzyme responsible for its degradation, were studied under normal and stress conditions in two lines of Drosophila virilis which are in contrast concerning their DA content under normal conditions and its alterations under stress. Interlinear differences in DDC activity were detected, and genetic analysis was carried out. It was found out that neither DDC nor NAT activity in D. virilis changed under stress. Based on the results of this study and data obtained earlier by the authors, a mechanism of DA content control under normal and stress conditions was proposed.
ISSN:0965-1748
1879-0240
DOI:10.1016/S0965-1748(97)00051-9