Severe oral ulceration in patients with HIV infection: A case series

OBJECTIVE: Oral ulceration occurs in an estimated 2–4% of patients with HIV infection. This retrospective observational study describes the aetiology and characteristics of 94 HIV‐positive patients with either severe and/or recurrent oral ulceration presenting at a dedicated HIV dental unit over a 4...

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Bibliographic Details
Published in:Oral diseases 1997-05, Vol.3 (S1), p.S194-S196
Main Authors: Zakrzewska, JM, Robinson, P, Williams, IG
Format: Article
Language:English
Subjects:
Acquired Immunodeficiency Syndrome - complications
Adult
AIDS/HIV
Clinical Protocols
Decision Trees
Dentistry
Diagnosis, Differential
Female
HIV Infections - complications
HIV/AIDS case series
Humans
Male
Oral Ulcer - diagnosis
Oral Ulcer - etiology
Oral Ulcer - pathology
Oral Ulcer - therapy
oral ulceration
Patient Care Planning
Retrospective Studies
thalidomide
Thalidomide - therapeutic use
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Summary:OBJECTIVE: Oral ulceration occurs in an estimated 2–4% of patients with HIV infection. This retrospective observational study describes the aetiology and characteristics of 94 HIV‐positive patients with either severe and/or recurrent oral ulceration presenting at a dedicated HIV dental unit over a 4‐year period. METHODS: Case records were reviewed for diagnosis investigations, CD4 count, CDC stage and treatment modality. RESULTS: Of the 94 patients 50% had an AIDS diagnosis. In patients with asymptomatic HIV disease minor recurrent oral ulceration was the commonest diagnosis whilst large non‐specific neutropenic ulcers were more frequently seen in patients with symptomatic disease with low CD4 counts. A variety of treatment modalities were used including thalidomide. An algorithm is presented for the management of patients with severe oral ulceration.
ISSN:1354-523X
1601-0825
DOI:10.1111/j.1601-0825.1997.tb00359.x