Pregnancy resulting from frozen-thawed embryos achieved by intracytoplasmic injection of cryopreserved sperm cells extracted from an orchidectomized, seminoma-bearing testis, causing obstructive azoospermia

A clinical pregnancy occurred in a 26-year-old patient after transfer of frozen-thawed embryos had been achieved by intracytoplasmic sperm injection (ICSI) of cryopreserved spermatozoa. These had been obtained from a testis removed due to seminoma. The couple applied to our fertility clinic for sper...

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Bibliographic Details
Published in:Human reproduction (Oxford) 1997-12, Vol.12 (12), p.2836-2838
Main Authors: Yavetz, H, Hauser, R, Botchan, A, Azem, F, Yovel, I, Lessing, J B, Amit, A, Yogev, L
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Birth control
Cryopreservation
Female
Fertilization in Vitro - methods
Gynecology. Andrology. Obstetrics
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Microinjections
Oligospermia - etiology
Oligospermia - therapy
Orchiectomy
Pregnancy
Pregnancy Outcome
Radiotherapy
Seminoma - complications
Seminoma - pathology
Seminoma - therapy
Spermatozoa
Sterility. Assisted procreation
Testicular Neoplasms - complications
Testicular Neoplasms - pathology
Testicular Neoplasms - therapy
Testis - cytology
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Summary:A clinical pregnancy occurred in a 26-year-old patient after transfer of frozen-thawed embryos had been achieved by intracytoplasmic sperm injection (ICSI) of cryopreserved spermatozoa. These had been obtained from a testis removed due to seminoma. The couple applied to our fertility clinic for sperm cryopreservation before orchidectomy and radiotherapy. Unfortunately the husband was found to be azoospermic upon admission and sperm cells were extracted from the removed testis for use in our ICSI programme. This case represents a new aetiology for obstructive azoospermia that was successfully treated by ICSI. A pregnancy was established, resulting in successful birth.
ISSN:0268-1161
1460-2350
DOI:10.1093/humrep/12.12.2836