Neosporosis and bovine abortion in Scotland

• Published in: Veterinary record 1997-12, Vol.141 (25), p.649-651
• Main Authors: Buxton, D., Caldow, G. L., Maley, S. W., Marks, J., Innes, E. A.
• Format: Article
• Language: English
• Subjects: abortion; Abortion, Septic - epidemiology; Abortion, Septic - veterinary; Abortion, Veterinary - epidemiology; Abortion, Veterinary - etiology; Abortion, Veterinary - parasitology; Animals; Antibodies, Protozoan - blood; Antigens, Protozoan - blood; Antigens, Protozoan - immunology; blood serum; Cattle; Cattle Diseases - epidemiology; Cattle Diseases - etiology; Cattle Diseases - transmission; Coccidiosis - epidemiology; Coccidiosis - transmission; Coccidiosis - veterinary; cows; Female; Fetal Diseases - epidemiology; Fetal Diseases - veterinary; fetus; Fluorescent Antibody Technique, Indirect - veterinary; immunoglobulin G; Immunoglobulin G - blood; immunoglobulin M; Immunoglobulin M - blood; Incidence; Infectious Disease Transmission, Vertical - veterinary; Neospora - immunology; Neospora caninum; Pregnancy; Pregnancy Complications, Parasitic - epidemiology; Pregnancy Complications, Parasitic - veterinary; Scotland - epidemiology; vertical transmission
• ISSN: 0042-4900; 2042-7670
• DOI: 10.1136/vr.141.25.649

Serum samples were collected over a two-year period from aborting cows and their fetuses from throughout Scotland; 465 maternal sera were examined using an immunofluorescent antibody test for IgG antibody to Neospora caninum and 547 fetal sera were examined for IgM and IgG antibody to the parasite; 355 of the maternal sera were paired with their respective fetal samples. The maternal titres ranged from 1/8 to 1/16,384, with 59 per cent (275) having titres of 1/128 or 1/256. Of the 547 fetal sera, 9.9 per cent had IgM titres equal to or greater than 1/64, 11.2 per cent had IgG titres equal to or greater than 1/64 and 15.9 per cent had IgM and/or IgG titres equal to or greater than 1/64. It is concluded that a fetal IgM or IgG titre of 1/64 or more is evidence of fetal exposure to N caninum but that the examination of maternal sera is less reliable on an individual basis, although valuable for indicating the degree of infection in a herd. Although fetal seropositivity does not necessarily provide proof that N caninum was the cause of death in a given case, the observation that 15.9 per cent of aborted fetuses had antibody to the parasite shows that vertical transmission from dam to fetus is relatively common and may be an important cause of fetal loss in cattle in Scotland.