Oral sources of septicaemia in patients with malignancies

This article reviews papers dealing with oral infections of adult septicaemia patients, searched from MEDLINE, Current Contents and Core Biomedical Collection databases from January 1966 to November 1996. Case reports were excluded. The systematic review of literature revealed that our knowledge of...

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Bibliographic Details
Published in:Oral oncology 1997-11, Vol.33 (6), p.389-397
Main Authors: Meurman, J.H., Pyrhönen, S., Teerenhovi, L., Lindqvist, C.
Format: Article
Language:English
Subjects:
Adult
antineoplastic agents
bacterial infections
Biological and medical sciences
cancer
Dental Care
Dental Plaque
Drug toxicity and drugs side effects treatment
Humans
Immunocompromised Host
immunosuppression
Medical sciences
Mouth - microbiology
mouth diseases
Mouth Diseases - complications
Mouth Diseases - therapy
Neoplasms - complications
Neoplasms - immunology
Neoplasms - therapy
oral health care
Oral Hygiene
Pharmacology. Drug treatments
Saliva
Sepsis - etiology
Sepsis - prevention & control
septicaemia
Toxicity: respiratory system, ent, stomatology
xerostomia
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Summary:This article reviews papers dealing with oral infections of adult septicaemia patients, searched from MEDLINE, Current Contents and Core Biomedical Collection databases from January 1966 to November 1996. Case reports were excluded. The systematic review of literature revealed that our knowledge of the topic is mostly based on very small patient material. There are no multicentre studies on the effects of various oral health treatment modes on the prevention of septicaemia of oral origin. The number of controlled and comparative studies on the efficacy of the different treatment protocols of oral infections is also small. Current recommendations in this respect are mainly empirical and not evidence based. Clinical practice guidelines are therefore urgently needed. Nevertheless, close co-operation between oncological and oral health units is emphasised because many studies have shown that the oral cavity is indeed an important source of bacteraemia. Life-threatening infections may follow if maintenance of oral health is neglected during anticancer therapy and if potential oral infection foci are left untreated before immunosuppressive therapy.
ISSN:1368-8375
1879-0593
DOI:10.1016/S0964-1955(97)00032-8