Sciatic nerve palsy following uneventful sciatic nerve block

We describe the loss of function in the sciatic nerve after an uneventful sciatic nerve block using 25 ml of lignocaine 1% with adrenaline 1 in 200 000 in a patient receiving β blocker drugs. Lack of pain on injection and complete regeneration of the nerve after 12 months in a patient with severe pe...

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Bibliographic Details
Published in:Anaesthesia 1997-12, Vol.52 (12), p.1205-1207
Main Authors: Bonner, S. M., Pridie, A. K.
Format: Article
Language:English
Subjects:
Anaesthetic techniques, regional
sciatic nerve block
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Complications
Female
Follow-Up Studies
Humans
Ischemia - complications
Local anesthesia. Pain (treatment)
Medical sciences
Middle Aged
Nerve Block - adverse effects
Nerve Regeneration
Paralysis - etiology
Sciatic Nerve - blood supply
Sciatic Nerve - physiology
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Description
Summary:We describe the loss of function in the sciatic nerve after an uneventful sciatic nerve block using 25 ml of lignocaine 1% with adrenaline 1 in 200 000 in a patient receiving β blocker drugs. Lack of pain on injection and complete regeneration of the nerve after 12 months in a patient with severe peripheral vascular disease led us to postulate ischaemic nerve damage as a mechanism of injury. Adrenaline‐induced unopposed α‐mediated vasoconstriction in a β‐blocked patient is suggested as a possible mechanism of peripheral nerve injury worthy of further investigation.
ISSN:0003-2409
1365-2044
DOI:10.1111/j.1365-2044.1997.258-az0396.x