Strategies in the surgical management of malignant gliomas

The overall prognosis for patients with malignant gliomas remains poor. The infiltrative nature of the tumor into normal brain and the presence of tumor foci in regions remote from the main tumor burden make cure with current therapies virtually impossible. Management therefore consists of tumor con...

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Bibliographic Details
Published in:Seminars in surgical oncology 1998-01, Vol.14 (1), p.26-33
Main Authors: Harbaugh, Kimberly S., Black, Peter M.
Format: Article
Language:English
Subjects:
biopsy
Biopsy - methods
brachytherapy
Brain Neoplasms - diagnosis
Brain Neoplasms - pathology
Brain Neoplasms - surgery
brain neoplasms/surgery/diagnosis/pathology
Clinical Protocols
craniotomy
Craniotomy - methods
glioma
Glioma - diagnosis
Glioma - pathology
Glioma - surgery
Humans
Magnetic Resonance Imaging
radiosurgery
Reoperation
Stereotaxic Techniques
survival rate
Tomography, X-Ray Computed
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Summary:The overall prognosis for patients with malignant gliomas remains poor. The infiltrative nature of the tumor into normal brain and the presence of tumor foci in regions remote from the main tumor burden make cure with current therapies virtually impossible. Management therefore consists of tumor control while maintaining the patient's quality of life. Surgery comprises only one arm of the overall treatment plan. Biopsy allows diagnosis and tumor grading even when tumors are located in eloquent or deep areas of brain. Craniotomy decreases overall tumor burden and provides room for the normal brain, edema and recurrent tumor. Many adjuncts are available to assist in gaining surgical access to tumors with minimal violation of normal functioning brain. Important among these are stereotaxy and surgery within a specially designed magnetic resonance scanner. The strategies for the surgical management of malignant gliomas utilized at our institution will be discussed. Semin. Surg. Oncol. 14:26–33, 1998. © 1998 Wiley‐Liss, Inc.
ISSN:8756-0437
1098-2388
DOI:10.1002/(SICI)1098-2388(199801/02)14:1<26::AID-SSU4>3.0.CO;2-4