Comparison of Computer Simulated and Phantom Measured Phase Variance in the Study of Trabecular Bone

A new method using magnetic resonance phase images for the assessment of trabecular bone structure has recently been proposed. To test this method, a mathematical model is developed which calculates the phase distribution in gradient echo acquired phase images of a structure of Pyrex glass rods imme...

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Bibliographic Details
Published in:Magnetic resonance imaging 1998, Vol.16 (1), p.29-36
Main Authors: Mihalopoulou, Evangelia, Allein, Sophie, Luypaert, Robert, Eisendrath, Henri, Bezerianos, Anastasios, Panayiotakis, George
Format: Article
Language:English
Subjects:
Biological and medical sciences
Bone and Bones - anatomy & histology
Bone Density
Computer Simulation
Humans
Investigative techniques, diagnostic techniques (general aspects)
Magnetic resonance
Magnetic Resonance Imaging
Medical sciences
Models, Theoretical
Osteoarticular system. Muscles
Phantoms, Imaging
Phase imaging
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Trabecular bone
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Summary:A new method using magnetic resonance phase images for the assessment of trabecular bone structure has recently been proposed. To test this method, a mathematical model is developed which calculates the phase distribution in gradient echo acquired phase images of a structure of Pyrex glass rods immersed in a copper sulfate solution. Several experiments were performed using a phantom built in the same way as the structure used in the mathematical model. The results from the model are compared with those from the phantom tests, and the influence of resolution and bone area fraction on the phase dispersion is studied. The good correlation between theoretical and experimental results shows that phase variance increases with increasing resolution and bone density. However, the dependence of variance on bone density is less prominent for large pixel sizes.
ISSN:0730-725X
1873-5894
DOI:10.1016/S0730-725X(97)00218-X