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Rickets and metabolic disorders

To the Editor.— The short report of Morrison and Kerr1 entitled "Growth Plate: Roentgenologic Findings in a Case of Tyrosinosis" deserves some comments. In addition to phenylketonuria and homocystinuria which were mentioned by the authors, roentgenologic bony changes were shown recently in...

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Bibliographic Details
Published in:Pediatrics (Evanston) 1990-04, Vol.85 (4), p.624-625
Main Authors: Ozsoylu, S, Besim, A
Format: Article
Language:English
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Summary:To the Editor.— The short report of Morrison and Kerr1 entitled "Growth Plate: Roentgenologic Findings in a Case of Tyrosinosis" deserves some comments. In addition to phenylketonuria and homocystinuria which were mentioned by the authors, roentgenologic bony changes were shown recently in a 5-month-old boy with mucolipidosis II (I-cell disease).2 Alkaline phosphatase was found to be elevated, and calcium and phosphorus levels were somewhat decreased in most of these cases. With the addition of roentgenologic findings one can be sure that all of these patients had rickets.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.85.4.624a