Ikirara, a novel transposon family from the malaria vector mosquito, Anopheles gambiae

Members of a novel transposon family, Ikirara, were found in the genome of the malaria vector Anopheles gambiae. They are most abundant in A. gambiae sensu stricto, but related sequences were found in all four other tested members of this species complex. No relatives were found in A. funestus or A....

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Bibliographic Details
Published in:Insect molecular biology 1998-02, Vol.7 (1), p.1-10
Main Authors: Romans, P, Bhattacharyya, R.K, Colavita, A
Format: Article
Language:English
Subjects:
Animals
Anopheles - genetics
Anopheles gambiae
Base Sequence
chromosome mapping
copy number
DNA
DNA Transposable Elements
genbank/u55049
gene location
Genes, Insect
genomics
Insect Proteins - genetics
Insect Vectors - genetics
inverted repeats
Malaria - transmission
Molecular Sequence Data
nucleic acid hybridization
nucleotide sequences
repetitive sequences
transposons
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Summary:Members of a novel transposon family, Ikirara, were found in the genome of the malaria vector Anopheles gambiae. They are most abundant in A. gambiae sensu stricto, but related sequences were found in all four other tested members of this species complex. No relatives were found in A. funestus or A. stephensi. Ikirara1, the first isolated family member, was found between two of the tandem Vitellogenin (Vg) genes. Because it was found at this location in G3 and only one of nine other A. gambiae s.s. strains examined, and because its 216 bp inverted terminal repeats are 100% identical, transposition to this locus may have been recent. Ikirara1 inverted repeat terminal sequences are similar to those of DNA to DNA transposons of the mariner/Tc1 and hAT superfamilies. Also similar to mariner/Tc1 elements, insertion of Ikirara1 apparently created a duplication of the dinucleotide TA at the target site.
ISSN:0962-1075
1365-2583
DOI:10.1046/j.1365-2583.1998.71046.x