Beyond inflammation: site-directed immunotherapy

As new biological therapies are devised, finer control over their delivery to local sites of disease or injury is needed. Migratory leukocytes are attractive vehicles for therapeutic agents. However, to exploit them fully, more information is required on the control of cell movement to local sites o...

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Bibliographic Details
Published in:Immunology today (Amsterdam. Regular ed.) 1998, Vol.19 (1), p.17-22
Main Author: Lampson, Lois A.
Format: Article
Language:English
Subjects:
Animals
Brain - physiology
Cell Movement
Humans
Immunotherapy
Inflammation - immunology
Major Histocompatibility Complex
T-Lymphocytes - physiology
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Summary:As new biological therapies are devised, finer control over their delivery to local sites of disease or injury is needed. Migratory leukocytes are attractive vehicles for therapeutic agents. However, to exploit them fully, more information is required on the control of cell movement to local sites of microscopic disease. Here, Lois Lampson suggests that the brain, with its low immunological background and varied microenvironments, can yield some useful insights.
ISSN:0167-5699
DOI:10.1016/S0167-5699(97)01181-X