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Age-related changes in rat liver phospholipid transfer activity

The age-induced changes in the liver cytosol phospholipid transfer activity of male and female rats have been investigated. These changes were found to be closely related to the age-induced alterations in the two major microsomal phospholipids — phosphatidylcholine and phosphatidylethanolamine. Regr...

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Published in:Experimental gerontology 1990, Vol.25 (1), p.55-60
Main Authors: Markovska, Tania T., Petkova, Diana H., Momchilova-Pankova, A.B., Koumanov, K.S.
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cited_by cdi_FETCH-LOGICAL-c416t-22ce9882c2b613c52cd561030e94528298146999e500bba7196a2772fc50ba23
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creator Markovska, Tania T.
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description The age-induced changes in the liver cytosol phospholipid transfer activity of male and female rats have been investigated. These changes were found to be closely related to the age-induced alterations in the two major microsomal phospholipids — phosphatidylcholine and phosphatidylethanolamine. Regression analysis indicated a linear correlation between the phospholipid transfer activity and the level of phosphatidylcholine (positive) and phosphatidylethanolamine (negative) in liver microsomes of both male and female rats.
doi_str_mv 10.1016/0531-5565(90)90009-Q
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source ScienceDirect
subjects aging
Aging - metabolism
Animals
Biological and medical sciences
Carrier Proteins - metabolism
Cytosol - metabolism
Female
Fundamental and applied biological sciences. Psychology
Liver - cytology
Liver - metabolism
Liver. Bile. Biliary tracts
Male
Membrane Lipids - metabolism
phosphatidylcholine
Phosphatidylcholines - metabolism
phosphatidylethanolamine
Phosphatidylethanolamines - metabolism
phospholipid transfer activity
Phospholipids - metabolism
Rats
Rats, Inbred Strains
Vertebrates: digestive system
title Age-related changes in rat liver phospholipid transfer activity
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