Hepatitis G Virus Infection in Screened Chinese Blood Donors

Background and Objectives: To determine the prevalence of the recently identified hepatitis G virus (HGV)/GBV‐C in screened Chinese paid blood donors. Materials and Methods: Two hundred and seventy‐nine plasma samples were tested for HGV RNA by RT‐PCR with nested primers from the 5'‐noncoding r...

Full description

Saved in:
Bibliographic Details
Published in:Vox sanguinis 1998-01, Vol.74 (1), p.51-52
Main Authors: Ren, Fu-Rong, Wang, Yu, Li, Hui, Chen, Hong-Song, Zhao, Hai-Yan
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood Donors
Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis
China - epidemiology
Flaviviridae - genetics
Hepatitis, Viral, Human - blood
Hepatitis, Viral, Human - epidemiology
Hepatitis, Viral, Human - genetics
Humans
Medical sciences
Polymerase Chain Reaction
Prevalence
RNA, Viral - blood
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background and Objectives: To determine the prevalence of the recently identified hepatitis G virus (HGV)/GBV‐C in screened Chinese paid blood donors. Materials and Methods: Two hundred and seventy‐nine plasma samples were tested for HGV RNA by RT‐PCR with nested primers from the 5'‐noncoding region of GBV‐C. All samples were obtained from plasma or blood bags that had been screened twice by routine selection tests (ALT, HBsAg, Anti‐HCV, anti‐HIV, and syphilis) and were available for clinical use. Results: HGV RNA was detected in 2 (4%) of 50 paid plasma donors from the Beijing Red Cross Blood Center, 1 (2%) of 50 paid blood donors from Taiyuan, and 9 (5%) of 179 paid blood donors from Hebei, a total HGV detection rate of 4.3% (12/279). Conclusions: Our data suggest that HGV infection is relatively frequent even in screened donors, at least in paid screened donors, although larger‐scale studies are required.
ISSN:0042-9007
1423-0410
DOI:10.1046/j.1423-0410.1998.7410051.x