Efficacy of moxidectin 2% equine gel against natural nematode infections in ponies

The efficacy of moxidectin 2% oral gel (Equest®, Fort-Dodge) against European worm strains was studied through post-mortem worm counts and feacal egg counts (FECs) in 12 young ponies naturally infected. The animals were allocated in two groups of six ponies each: the first one was treated at 0.4 mg/...

Full description

Saved in:
Bibliographic Details
Published in:Veterinary parasitology 1998-01, Vol.74 (1), p.85-89
Main Authors: Dorchies, P., Ducos de Lahitte, J., Flochlay, A., Blond-Riou, F.
Format: Article
Language:English
Subjects:
Animals
Anthelmintics - administration & dosage
Anthelmintics - therapeutic use
Anti-Bacterial Agents
Control methods—Nematoda
Cyathostomes
Feces - parasitology
Gasterophilus intestinalis
Gels
Habronema spp
Horse
Horse Diseases
Horses
Macrolides - administration & dosage
Macrolides - therapeutic use
Male
Moxidectin
Nematode Infections - diagnosis
Nematode Infections - prevention & control
Nematode Infections - veterinary
Oxyuris equi
Parascaris equorum
Parasite Egg Count - veterinary
Strongylus edentatus
Trichostrongylus axei
Triodontophorus spp
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The efficacy of moxidectin 2% oral gel (Equest®, Fort-Dodge) against European worm strains was studied through post-mortem worm counts and feacal egg counts (FECs) in 12 young ponies naturally infected. The animals were allocated in two groups of six ponies each: the first one was treated at 0.4 mg/kg b.w. and the second one received a placebo and served as control. All the ponies were necropsied 14 days post-treatment. The efficacy of moxidectin in reducing strongyle FECs ranged from 99.8% to 100% from 3 to 14 days after treatment. Moxidectin efficacy was 100% against Trichostrongylus axei and Triodontophorus spp., > 99.9% against Cyathostomes adults and L5, 92% against S. edentatus L5, 100% against O. equi L5, 99% against O. equi L4, and 92% against G. intestinalis. No animal treated with moxidectin was harbouring P. equorum, Habronema spp., G. pecorum nor G. nasalis, while the control group was slightly infected with these parasites. This experiment confirms the post-mortem worm count results obtained in the United States and the FECs results reported in Europe. Moxidectin showed to be safe in young ponies.
ISSN:0304-4017
1873-2550
DOI:10.1016/S0304-4017(97)00144-1