Placental IGF‐I in severe intrauterine growth retardation

IGF‐I, which is produced by intrauterine tissues including the placenta, has been implicated as a possible factor in intrauterine growth retardation (IUGR). We hypothesized that placental IGF‐I production may be aberrant in pregnancies affected by IUGR. A placental perifusion system was utilized to...

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Bibliographic Details
Published in:The Journal of maternal-fetal medicine 1998-01, Vol.7 (1), p.1-7
Main Authors: Sorem, K.A., Siler‐Khodr, T.M.
Format: Article
Language:English
Subjects:
Female
Fetal Growth Retardation - metabolism
human
Humans
IGF‐I
Insulin-Like Growth Factor I - metabolism
IUGR
Kinetics
Perfusion
placenta
Placenta - metabolism
Pregnancy
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Summary:IGF‐I, which is produced by intrauterine tissues including the placenta, has been implicated as a possible factor in intrauterine growth retardation (IUGR). We hypothesized that placental IGF‐I production may be aberrant in pregnancies affected by IUGR. A placental perifusion system was utilized to study the release of IGF‐I in placentas from normotensive severe IUGR (birthweight
ISSN:1057-0802
1520-6661
DOI:10.1002/(SICI)1520-6661(199801/02)7:1<1::AID-MFM1>3.0.CO;2-S