Is Xenotransplantability of Human Colon Cancers in SCID Mice Affected by Angiogenic Factors?

Since Rygaard and Povlsen reported the successful transplantation of human malignant tumors into nude mice, various type of human tumors have been maintained in these mice. However, it is not clearly understood what key properties and molecules of donor tumor lead to successful establishment of xeno...

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 1998-03, Vol.90 (5), p.400-401
Main Authors: Tokunaga, Tetsuji, Nakamura, Masato, Oshika, Yoshiro, Ueyama, Yoshito, Ohnishi, Yasuyuki
Format: Article
Language:English
Subjects:
Animals
Colon cancer
Colonic Neoplasms - pathology
Colonic Neoplasms - surgery
Female
Gene Expression Regulation, Neoplastic
Humans
Male
Mice
Mice, SCID
Middle Aged
Neoplasms, Experimental - pathology
Neovascularization, Pathologic
Rodents
Transplantation, Heterologous
Xenotransplantation
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Description
Summary:Since Rygaard and Povlsen reported the successful transplantation of human malignant tumors into nude mice, various type of human tumors have been maintained in these mice. However, it is not clearly understood what key properties and molecules of donor tumor lead to successful establishment of xenografts.
ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/90.5.400