Analysis of biological reference materials, prepared by microwave dissolution, using inductively coupled plasma mass spectrometry

A procedure has been developed for the analysis of biological materials by inductively coupled plasma mass spectrometry (ICP-MS). Fast, efficient and complete sample digestion is achieved by a combined microwave-nitric acid/open beaker-nitric acid-hydrogen peroxide procedure. The ICP-MS analysis is...

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Bibliographic Details
Published in:Analyst (London) 1990-03, Vol.115 (3), p.269-273
Main Authors: Friel, J K, Skinner, C S, Jackson, S E, Longerich, H P
Format: Article
Language:English
Subjects:
Animals
Liver - analysis
Mass Spectrometry - methods
Mass Spectrometry - standards
Metals - analysis
Microwaves
Muscles - analysis
Ostreidae - analysis
Quality Control
Reference Standards
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Summary:A procedure has been developed for the analysis of biological materials by inductively coupled plasma mass spectrometry (ICP-MS). Fast, efficient and complete sample digestion is achieved by a combined microwave-nitric acid/open beaker-nitric acid-hydrogen peroxide procedure. The ICP-MS analysis is performed with an on-line five-element internal standard to correct for matrix and instrumental drift effects. Results are presented for 24 elements in three biological reference materials (National Institute of Standards and Technology Standard Reference Materials 5277a Liver and 1566 Oyster and International Atomic Energy Agency Certified Reference Material H4 Animal Muscle). For all elements significantly above the detection limit and reagent blank concentrations, good agreement exists between ICP-MS and certified values.
ISSN:0003-2654
1364-5528
DOI:10.1039/AN9901500269