Ischemic Colitis: Tc-99m HMPAO Leukocyte Scintigraphy and Correlative Imaging

A 62-year-old woman became progressively ill after aorto-bifemoral graft surgery. A Tc-99m hexamethylpropyleneamine oxime (HMPAO) leukocyte scan was performed because of fever and suspected graft infection. The anterior abdominal and pelvic views demonstrated marked uptake within the sigmoid colon....

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Bibliographic Details
Published in:Clinical nuclear medicine 1998-03, Vol.23 (3), p.165-167
Main Authors: HYUN, HYEWON, PAI, EUGENE, BLEND, MICHAEL J
Format: Article
Language:English
Subjects:
Aorta, Abdominal - surgery
Biological and medical sciences
Colitis, Ischemic - diagnostic imaging
Colitis, Ischemic - etiology
Digestion. Liver. Biliary tract. Spleen. Pancreas
Female
Femoral Artery - surgery
Humans
Investigative techniques, diagnostic techniques (general aspects)
Leukocytes
Medical sciences
Middle Aged
Postoperative Complications
Radionuclide Imaging
Radionuclide investigations
Radiopharmaceuticals
Technetium Tc 99m Exametazime
Tomography, X-Ray Computed
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Summary:A 62-year-old woman became progressively ill after aorto-bifemoral graft surgery. A Tc-99m hexamethylpropyleneamine oxime (HMPAO) leukocyte scan was performed because of fever and suspected graft infection. The anterior abdominal and pelvic views demonstrated marked uptake within the sigmoid colon. Follow-up studies, including CT scan and contrast intestinal x-rays, confirmed the presence of an abnormal sigmoid loop. Subsequent surgical resection and pathological examination of the sigmoid colon revealed ischemic changes. To our knowledge, detection of ischemic colitis using Tc-99m HMPAO labeled leukocytes has not been reported. Clinical and routine radiological findings of ischemic colitis are typically nonspecific and may result in delayed diagnosis that can lead to high mortality. Tc-99m HMPAO leukocyte scintigraphy may be helpful in the noninvasive diagnosis of ischemic injury to the colon, especially after aortic graft surgery.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199803000-00008