No evidence of HCV infection or liver disease in British patients with oral lichen planus

An association between chronic hepatic disease and/or hepatitis C (HCV) infection and lichen planus (LP) has been described in patients from Italy, Japan and Spain. There are no data on the frequency of the association with HCV in British patients. In the present investigation, the HCV seropositivit...

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Bibliographic Details
Published in:International journal of oral and maxillofacial surgery 1998-02, Vol.27 (1), p.65-66
Main Authors: Ingafou, M., Porter, S.R., Scully, C., Teo, C.G.
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Case-Control Studies
Dentistry
Female
Hepatitis C - blood
Hepatitis C - complications
Hepatitis C - epidemiology
Hepatitis C Antibodies - blood
Humans
Lichen Planus, Oral - complications
Lichen Planus, Oral - epidemiology
Liver Diseases - epidemiology
Liver Function Tests
Male
Medical sciences
Middle Aged
Non tumoral diseases
Otorhinolaryngology. Stomatology
United Kingdom - epidemiology
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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Description
Summary:An association between chronic hepatic disease and/or hepatitis C (HCV) infection and lichen planus (LP) has been described in patients from Italy, Japan and Spain. There are no data on the frequency of the association with HCV in British patients. In the present investigation, the HCV seropositivity and liver function status of 55 British patients with oral LP were assessed and compared with these parameters in 110 healthy control subjects. None of the patients with LP or control subjects had serum IgG antibodies to HCV or had abnormal liver function. It was concluded that while LP may be associated with HCV infection and liver disease in some southern European and other patients, such a co-occurence was not detected in British patients.
ISSN:0901-5027
1399-0020
DOI:10.1016/S0901-5027(98)80101-X