Cytotoxic activity of selected plants used as antitumorals in Mexican traditional medicine

Crude extracts from nine plants widely used in Mexican traditional medicine for the treatment of cancer have been subjected to a bioscreening study to detect cytotoxic activity against human tumor cells. Three different extracts (petroleum ether, ethylacetate, and methanol) from each plant species,...

Full description

Saved in:
Bibliographic Details
Published in:Journal of ethnopharmacology 1998, Vol.59 (3), p.173-177
Main Authors: Popoca, Jovita, Aguilar, Abigaı́l, Alonso, Daniel, Villarreal, Ma.Luisa
Format: Article
Language:English
Subjects:
antineoplastic agents
Antineoplastic Agents, Phytogenic - pharmacology
Antitumor
Biological and medical sciences
Cytotoxic
cytotoxic compounds
Folk medicine
General pharmacology
Humans
Medical sciences
Medicinal plants
Medicine, Traditional
Mexico
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plants, Medicinal - chemistry
Tumor Cells, Cultured
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Crude extracts from nine plants widely used in Mexican traditional medicine for the treatment of cancer have been subjected to a bioscreening study to detect cytotoxic activity against human tumor cells. Three different extracts (petroleum ether, ethylacetate, and methanol) from each plant species, were tested towards KB, HCT-15 COLADCAR and UISO-SQC-1 cell cultures. The results showed that three plants Colubrina macrocarpa (Cav.) Don (Rhamnaceae), Acacia pennatula (Schltdl. and Cham.) Benth (Leguminosae) and Hemiangium excelsum (HBK.) Smith (Hippocrateaceae), exhibited important cytotoxic activity showing a certain degree of selectivity against the tested cells in culture.
ISSN:0378-8741
1872-7573
DOI:10.1016/S0378-8741(97)00110-4