PREDICTIVE VALUE OF FRC AND RESPIRATORY COMPLIANCE ON PULMONARY GAS EXCHANGE INDUCED BY HIGH FREQUENCY JET VENTILATION IN HUMANS

To determine if functional residual capacity (FRC), compliance of the respiratory system (C), or underlying pulmonary disease are predictive for the efficacy of high frequency jet ventilation (HFJV) on pulmonary gas exchange, we investigated six adult patients within 4 h of abdominal surgery and six...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1990-04, Vol.64 (4), p.460-468
Main Authors: PITTET, J.F., MOREL, D.R., BACHMANN, M., FORSTER, A., SUTER, P.M.
Format: Article
Language:English
Subjects:
Abdomen - surgery
Adult
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
compliance
Emergency and intensive respiratory care
Female
Functional Residual Capacity - physiology
gas exchange
Hemodynamics - physiology
High-Frequency Jet Ventilation
Humans
Intensive care medicine
Intermittent Positive-Pressure Ventilation
Lung Compliance - physiology
Lung Volume Measurements
Lung: functional residual capacity
Male
Medical sciences
Middle Aged
Pulmonary Gas Exchange - physiology
Respiration - physiology
Respiratory Distress Syndrome, Adult - physiopathology
Ventilation: high frequency jet ventilation
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Summary:To determine if functional residual capacity (FRC), compliance of the respiratory system (C), or underlying pulmonary disease are predictive for the efficacy of high frequency jet ventilation (HFJV) on pulmonary gas exchange, we investigated six adult patients within 4 h of abdominal surgery and six patients with severe adult respiratory distress syndrome. Gas exchange during intermittent positive pressure ventilation (IPPV) was compared with that during HFJV at frequencies of 100 b.p.m. (HFJV100) and 200 b.p.m. (HFJV200), resulting in a minute ventilation of about 400 ml kg−1 with both ventilatory frequencies, and in both groups of patients. Baseline FRC and C were measured during IPPV with the multiple-breath nitrogen washout method and from expiratory pressure-volume curves, respectively. Changes in the alveolar-arterial oxygen difference (PAO2−PaO2): FlO2 ratio induced by HFJV correlated negatively with C (HFJV100: r = −0.78, P
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/64.4.460